DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment igsf9a and dpr3

DIOPT Version :9

Sequence 1:	XP_005155702.1	Gene:	igsf9a / 557459	ZFINID:	ZDB-GENE-060503-288	Length:	1619	Species:	Danio rerio
Sequence 2:	NP_001014459.2	Gene:	dpr3 / 3346208	FlyBaseID:	FBgn0053516	Length:	522	Species:	Drosophila melanogaster

Alignment Length:	392	Identity:	85/392 - (21%)
Similarity:	129/392 - (32%)	Gaps:	153/392 - (39%)

- Green bases have known domain annotations that are detailed below.

Zfish    18 LFNDTSAAEEHVRAKKDSSAVLPCSLPAPQKDSSASQYVIEWVRQGFDTPIF------------- 69
            ||..|.|..|...|..:.|           :|:..||          ..|||
  Fly   208 LFAQTDAKRERSGAADEES-----------QDADTSQ----------SLPIFDFGMPRNITGRTG 251

Zfish    70 -MQLGVHPRVHPDYDGRVS---------LFGGTSLQMSGLQLE--------------------DE 104
             .:..:..||...:|..||         |..||:...|..:.:                    |.
  Fly   252 HTEAIIKCRVDSLHDKSVSWIRKRDLHILTVGTATYTSDKRFQVTESKDSREWTLHVKAPLAKDS 316

Zfish   105 GWYECRILPLDQTTEEAGSSGSWTRLSVTAPPVLTETS-PPEVEVFVGRSLTLKCAAQGNPRPTI 168
            |.|||::     .||...|......:...:|......| ||::....|.::.|.|..|   :|::
  Fly   317 GIYECQV-----NTEPKMSMAFQLNIIEISPDAKAVISGPPDLHFKAGSAIILNCLVQ---QPSV 373

Zfish   169 TWSKDGAPI---KPQHKVKMVNGSVSFHAVSREAAGQYQCYTSNSEGNATHVTRLKIIGPPVIII 230
               ||..||   :.:|.:      ..|.|..    ||.:.    ..|...|        |..|
  Fly   374 ---KDIGPIYWYRGEHMI------TPFDADD----GQPEI----PAGRGEH--------PQGI-- 411

Zfish   231 PPSDTVLN--MSQ-DAKLKCQAEADPPNMTYVWQRQGVDIYHIDSLKSRIKVIVDGTLLISRLAP 292
             |.||..|  ||: |.:::...            |..::....|:||||::        ||....
  Fly   412 -PEDTSPNDIMSEVDLQMEFAT------------RIAMESQLGDTLKSRLR--------ISNAQT 455

Zfish   293 EDSGNYTCMPTNGLPVSPSASAVLTV---QHPA-------------------QVIQMPKLTFLPT 335
            .|:|||||.||    .:.|||.::.|   ::||                   .::.:|:|..|..
  Fly   456 TDTGNYTCQPT----TASSASVLVHVINDENPAAMQKSGACPCALGPLQLLLHLLLLPELLLLRA 516

Zfish   336 GM 337
            |:
  Fly   517 GL 518

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
igsf9a	XP_005155702.1	IG_like	27..110	CDD:214653	22/125 (18%)
		Ig	35..111	CDD:299845	21/118 (18%)
		I-set	140..221	CDD:254352	19/84 (23%)
		IGc2	151..212	CDD:197706	14/63 (22%)
		Ig	233..318	CDD:299845	25/87 (29%)
		I-set	233..318	CDD:254352	25/87 (29%)
		Ig	<349..402	CDD:299845
		IG_like	423..502	CDD:214653
		Ig	435..498	CDD:143165
		FN3	507..602	CDD:238020
		fn3	614..696	CDD:278470
		PHA02666	1105..>1312	CDD:222914
dpr3	NP_001014459.2	Ig	243..330	CDD:299845	16/91 (18%)
		IG_like	243..329	CDD:214653	16/90 (18%)
		Ig	350..464	CDD:299845	40/164 (24%)
		IG_like	<441..477	CDD:214653	18/47 (38%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.900