Protein Alignment PRKAR1A and Prkar1a

DIOPT Version :9

• Sequence 1: NP_001263218.1
• Gene: PRKAR1A / 5573
• HGNCID: 9388
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_037313.1
• Gene: Prkar1a / 25725
• RGDID: 3391
• Length: 381
• Species: Rattus norvegicus
• Alignment Length: 381
• Identity: 371/381 - (97%)
• Similarity: 375/381 - (98%)
• Gaps: 0/381 - (0%)

Human     1 MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQI 65
            |.|||.|||||.||||||||||||||||||||||||||||||||||||||||||||||||||:||
  Rat     1 MASGSMAASEEERSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEARQI 65

Human    66 QNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAK 130
            |:|||:|.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat    66 QSLQKSGIRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAK 130

Human   131 AIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVG 195
            ||||||||||||||||||||||||.||||||||||||||||||||||||||.|||||||||||||
  Rat   131 AIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVG 195

Human   196 EGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   196 EGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 260

Human   261 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFG 325
            ||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||
  Rat   261 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFG 325

Human   326 EIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
  Rat   326 EIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKAR1A	NP_001263218.1	Dimerization and phosphorylation	1..136		127/134 (95%)
		DD_RIalpha_PKA	14..63	CDD:213048	48/48 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..96		28/31 (90%)
		Pseudophosphorylation motif	96..100		3/3 (100%)
		CAP_ED	137..246	CDD:237999	106/108 (98%)
		CAP_ED	255..370	CDD:237999	113/114 (99%)
Prkar1a	NP_037313.1	Dimerization and phosphorylation	2..136		126/133 (95%)
		DD_RIalpha_PKA	14..63	CDD:213048	48/48 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	65..96		27/30 (90%)
		Pseudophosphorylation motif	96..100		3/3 (100%)
		CAP_ED	137..246	CDD:237999	106/108 (98%)
		CAP_ED	255..370	CDD:237999	113/114 (99%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83689166
Domainoid	1	1.000	178	1.000	Domainoid score	I27478
eggNOG	1	0.900	-	-		E1_COG0664
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H37664
Inparanoid	1	1.050	731	1.000	Inparanoid score	I8395
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54324
OrthoDB	1	1.010	-	-		D1047290at2759
OrthoFinder	1	1.000	-	-		FOG0000531
OrthoInspector	1	1.000	-	-		oto139855
orthoMCL	1	0.900	-	-		OOG6_100449
Panther	1	1.100	-	-	LDO	PTHR11635
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X421
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	17.310