Protein Alignment PRKAR1A and Prkar1a

DIOPT Version :10

• Sequence 1: NP_002725.1
• Gene: PRKAR1A / 5573
• HGNCID: 9388
• Length: 381
• Species: Homo sapiens
• Sequence 2: NP_068680.1
• Gene: Prkar1a / 19084
• MGIID: 104878
• Length: 381
• Species: Mus musculus
• Alignment Length: 381
• Identity: 369/381 - (96%)
• Similarity: 371/381 - (97%)
• Gaps: 0/381 - (0%)

Human     1 MESGSTAASEEARSLRECELYVQKHNIQALLKDSIVQLCTARPERPMAFLREYFERLEKEEAKQI 65
            |.|||.|.|||.||||||||||||||||||||||||||||.|||||||||||||||||||||:||
Mouse     1 MASGSMATSEEERSLRECELYVQKHNIQALLKDSIVQLCTTRPERPMAFLREYFERLEKEEARQI 65

Human    66 QNLQKAGTRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAK 130
            |.|||.|.|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    66 QCLQKTGIRTDSREDEISPPPPNPVVKGRRRRGAISAEVYTEEDAASYVRKVIPKDYKTMAALAK 130

Human   131 AIEKNVLFSHLDDNERSDIFDAMFSVSFIAGETVIQQGDEGDNFYVIDQGETDVYVNNEWATSVG 195
            ||||||||||||||||||||||||.||||||||||||||||||||||||||.|||||||||||||
Mouse   131 AIEKNVLFSHLDDNERSDIFDAMFPVSFIAGETVIQQGDEGDNFYVIDQGEMDVYVNNEWATSVG 195

Human   196 EGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 260
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   196 EGGSFGELALIYGTPRAATVKAKTNVKLWGIDRDSYRRILMGSTLRKRKMYEEFLSKVSILESLD 260

Human   261 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGSAAVLQRRSENEEFVEVGRLGPSDYFG 325
            ||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||||||
Mouse   261 KWERLTVADALEPVQFEDGQKIVVQGEPGDEFFIILEGTAAVLQRRSENEEFVEVGRLGPSDYFG 325

Human   326 EIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   326 EIALLMNRPRAATVVARGPLKCVKLDRPRFERVLGPCSDILKRNIQQYNSFVSLSV 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKAR1A	NP_002725.1	Dimerization and phosphorylation	1..136		125/134 (93%)
		DD_RIalpha_PKA	14..63	CDD:438522	47/48 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	64..96		28/31 (90%)
		Pseudophosphorylation motif	96..100		3/3 (100%)
		CAP_ED	137..246	CDD:237999	106/108 (98%)
		CAP_ED	255..370	CDD:237999	113/114 (99%)
Prkar1a	NP_068680.1	Dimerization and phosphorylation	2..136		124/133 (93%)
		DD_RIalpha_PKA	14..63	CDD:438522	47/48 (98%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	73..96		21/22 (95%)
		Pseudophosphorylation motif	96..100		3/3 (100%)
		CAP_ED	137..246	CDD:237999	106/108 (98%)
		CAP_ED	255..370	CDD:237999	113/114 (99%)