Protein Alignment kcnf1a and Shawl

DIOPT Version :9

• Sequence 1: NP_001076280.1
• Gene: kcnf1a / 557280
• ZFINID: ZDB-GENE-041001-217
• Length: 494
• Species: Danio rerio
• Sequence 2: NP_001097131.2
• Gene: Shawl / 5740840
• FlyBaseID: FBgn0085395
• Length: 937
• Species: Drosophila melanogaster
• Alignment Length: 565
• Identity: 147/565 - (26%)
• Similarity: 233/565 - (41%)
• Gaps: 175/565 - (30%)

Zfish    20 ETEISVNIGGVKHTLYGDVLNRYPETRLAELLNRVSDSAEDLSGLCDDYDDLKREFYFDRDPKAF 84
            |..|.:|:.|:::..|...|.:.|.|||:.|...::           :||.:..|::|||.|..|
  Fly     4 ENRIILNVSGIRYETYKATLKKIPATRLSRLTEALA-----------NYDPVLNEYFFDRHPGVF 57

Zfish    85 KCILELYYYGEIHMKRGICPMCFMKEMDYWGIDEDYLDECCRCSLN---EVETELAEIAEKVKTI 146
            ..||..|..|::|....:|...|.:|:::||:|.:.::.||..:.:   :.:..||        |
  Fly    58 TQILNYYRTGKLHYPTDVCGPLFEEELEFWGLDSNQVEPCCWSTYSIHRDTQNTLA--------I 114

Zfish   147 LDDLE-DDDDDDDARVSRS---------------QRCQTFLWKLMEKPESSVAARVIAVVSFVFI 195
            ||.|: :::...:.:::|.               ||.:..:|.:.::|.||..|:::|.:|..||
  Fly   115 LDKLDIENEKPTEEQIARLFGFEEALSNGELNCWQRIKPKIWAMFDEPSSSTGAKIVAGMSVFFI 179

Zfish   196 LLSSVVMCVGTIPELQVQDDEGHLTEH------------------------------------PT 224
            .:|.:..|:.|.|..:|....|....|                                    ||
  Fly   180 FVSVISFCLKTHPGFRVDLPSGAHDAHGPGAGGPPHGHDPMGEPPQTHQYHQHSITPPSGSIGPT 244

Zfish   225 LEA-------------------------------------------------------------- 227
            ...
  Fly   245 FRVTNYTSYSSGNFTASGQATPIATIKGGQRQRLKRNINGSILNEFIEEKILGHNGRRKHGWIET 309

Zfish   228 ----------IETACIIWFTVEYVLRLASSSSKLHFVFSFLNIIDFLAIMPFYVVLILTHLGTAM 282
                      :|..|.:||.:|.::||..|.:...|:.|.:|||||.|.:.||.        ..|
  Fly   310 YGQPHEAFFYVELVCNVWFFIEVIIRLIVSPNLWQFIKSPVNIIDFTATLSFYT--------DVM 366

Zfish   283 MELANVQQAVQALRIMRIARIFKLARHSSGLQTLTFALKSSLKELGLLLMYMSVGIFLFSALGYT 347
            ..:......::|..|:||.|:|||.|||.||:.|....|:|.|||.||:.::.:||..|::|.|.
  Fly   367 QRMGEYTGLLEAFSIVRIMRLFKLTRHSPGLRILIHTFKASAKELTLLVFFLVLGIVFFASLAYY 431

Zfish   348 ME--QSHPETMFTSIPQSFWWAIITMTTVGYGDIYPKTTLGRCNAAVSFLCGVIAIALPIHPIIN 410
            .|  |.:|:..|.|||...||||:|||||||||:.|||..|....|:..|.||:.||||:..|::
  Fly   432 AEKLQDNPDNQFKSIPLGLWWAIVTMTTVGYGDVAPKTYPGMFVGALCALAGVLTIALPVPVIVS 496

Zfish   411 NFVIVYSKQRVLETAAKHEIELMALRAREEAQECPEAERRAASVD 455
            ||.:.||     .|.|:.::              |:..||...|:
  Fly   497 NFSMFYS-----HTQARSKL--------------PKKRRRVLPVE 522

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
kcnf1a	NP_001076280.1	BTB_2	23..124	CDD:308049	29/100 (29%)
		Ion_trans	184..420	CDD:306908	96/345 (28%)
Shawl	NP_001097131.2	BTB	7..99	CDD:197585	30/102 (29%)
		BTB_2	7..97	CDD:280393	29/100 (29%)
		Ion_trans	307..506	CDD:278921	82/211 (39%)
		Ion_trans_2	<449..499	CDD:285168	27/49 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG2126
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D331021at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X19
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	5	4.820