Protein Alignment FAR2 and wat

DIOPT Version :10

• Sequence 1: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_651652.2
• Gene: wat / 43420
• FlyBaseID: FBgn0039620
• Length: 517
• Species: Drosophila melanogaster
• Alignment Length: 485
• Identity: 159/485 - (32%)
• Similarity: 272/485 - (56%)
• Gaps: 10/485 - (2%)

Human    22 STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFE 86
            |.:..||..|.:.:||.|||.||:::|||.|.: ::..||:|:|.|.|:....|:..:.:..:|.
  Fly    30 SPMQMFYKDKGVFLTGGTGFFGKIIIEKLLRVT-EVGQIYLLIRTKKGKDAFARIEDLFNDPVFA 93

Human    87 KVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTA 151
            |:|:|.|....:|..|..|.:.....||.::.:.::...||:.|.|||||||:.|:.|:.:||..
  Fly    94 KMKQVNPKYRCQITIISGDCSLPGLGISADERETIMENVNIVLHSAATVRFDEKLKMAIAINVHG 158

Human   152 TRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKL 216
            |::::.:|.::..|:|.:|:|||:::||::||.|..|...:..:......|.||:..::.:||.:
  Fly   159 TKEIIKLAKEIVNLKALVHVSTAFAHCNMRHIQERFYSGTMSGENAFKLSECLDEHTLNTLTPTI 223

Human   217 IRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGF 281
            |:.:||.||:||.|.|.||||.::||.:.|.||.||..|::||..||:||:.||.|:|:..|.|.
  Fly   224 IKGYPNTYTFTKVLAENVVQQSAQNLPVTIFRPGIVITTYREPVTGWIDNMYGPCGVIVGIGSGV 288

Human   282 LRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTLVYHITSGNMNPCNWHKMGVQVLATF 346
            ||.........|.::|||..||.:||..|..|.::.::..:|:......|...|.:   .:...|
  Fly   289 LRVFTGDMDNKAHIVPVDMCVNALLASAWDIARNKYETPPIYNYVPDAENMVTWRR---YMEDGF 350

Human   347 E---KIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRLLRTV 408
            |   .||..:....|......:.:.......:.|..||::.|..:.:.|:||||.|:..::.:..
  Fly   351 EYGCDIPMRKSIWYPRFTIVPHMWQYHILCFLYHTLPALVMDAIMVIIGKKPRMMKIYRKIHKLS 415

Human   409 SMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKEDMAGI 473
            ::|:||.:..:.:...|...|..:|...|:|:|.||:|.|:|.......:.|::.|::|:|.:.|
  Fly   416 NVLKYFSSNEFRFDNDNVRKLTEKLDDRDKRLFAFDMRDLDWTNLFRVSLYGLRLYVVKDDPSNI 480

Human   474 PKAKQRLKRLRNIHYLFNTALF--LIAWRL 501
            |::.:|.:||:.:||. ..|:|  |.||.|
  Fly   481 PESIKRYERLKVLHYT-TLAVFYALAAWAL 509

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	109/303 (36%)
		Sterile	377..467	CDD:460779	26/89 (29%)
wat	NP_651652.2	FAR-N_SDR_e	39..342	CDD:187547	109/303 (36%)
		FAR_C	382..472	CDD:176924	25/89 (28%)