Protein Alignment FAR2 and CG12268

DIOPT Version :10

• Sequence 1: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_651197.1
• Gene: CG12268 / 42833
• FlyBaseID: FBgn0039131
• Length: 531
• Species: Drosophila melanogaster
• Alignment Length: 531
• Identity: 182/531 - (34%)
• Similarity: 282/531 - (53%)
• Gaps: 41/531 - (7%)

Human    22 STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFE 86
            |.||.||..|:|||||||||:||||:|||.|:..||.|||:|:|.|.|.....|..|.....:|.
  Fly    13 SDIAKFYANKTILITGATGFMGKVLVEKLLRSCADLNVIYLLIRTKKGVDPSVRKEQYFKCVIFG 77

Human    87 KVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTA 151
            |:.|..|.:.:|:|.:..||.:.|..:|..|...|.|...::|||||.||||..||..|.:||..
  Fly    78 KLLEKNPGIVDKVRVVKGDLLEPDLGLSANDTNTLASNVEVVFHCAANVRFDQPLRPMVMMNVVG 142

Human   152 TRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPKL 216
            |.::|.:|.:|.:|:|.:|:||:|..||...::|..||.|..|..||:.:|.:||..:.||||||
  Fly   143 TLKVLRLAEKMSQLQALVHVSTSYCQCNESVLEERAYPAPQNPFSIIEMVETMDDEALAEITPKL 207

Human   217 IRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKGF 281
            :...||.|.|:|||.|.::.:.:..|.|.|.|||||.|...||.|||::.:|||.|::|...:|.
  Fly   208 LNGLPNTYAYSKALSEDLICRYNNKLPIIITRPSIVTAAIHEPLPGWIEGVNGPTGLMIGAARGV 272

Human   282 LRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTLVYHITSGNMNP----CN-------- 334
            :|::...|...:.|||||..:|.|:..|:    .|.|::.    ..||...    ||
  Fly   273 IRSMHCNPDYASTVIPVDKAINGMILCGY----QRGKASQ----EKGNKQTGVEFCNLCISSKAL 329

Human   335 --WHKMGVQVLATFEKIPFERPFR----RPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGR 393
              |.    ..:.|..:..:|.|..    .|..:...|.:...:.....|..||...|.:|.:.|:
  Fly   330 MSWG----DSIETGRRFFYETPLSFALWYPGGSIKKNYYHHLFCVIFFHYLPAYFIDFWLLVFGQ 390

Human   394 KPRMTKLMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYV 458
            ||.:..:..::...:.:|:|:..:.||:.....:.:.|:||..||.:|:..|.|:||..||.||:
  Fly   391 KPFLLNVQRKVSMGLKLLQYYTTKRWEFRNERFQEMSSQLSLLDQDLFDTSVGQVNWETYISNYI 455

Human   459 LGVKKYLLKEDMAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLIARSQMARNVWFFIVSFCYKF 523
            :|::.|:|.|....:|:|::.|:||..:.::.....|.:::..|          |..:..|..:.
  Fly   456 VGMRTYILGESEDTLPQARKVLRRLYILDWVSKVLFFSLSFWFL----------WTHLDGFVERS 510

Human   524 LSYFRAS-STL 533
            .::.|:| ||:
  Fly   511 DAFIRSSLSTI 521

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	128/317 (40%)
		Sterile	377..467	CDD:460779	28/89 (31%)
CG12268	NP_651197.1	FAR-N_SDR_e	22..347	CDD:187547	131/336 (39%)
		Sterile	373..463	CDD:460779	28/89 (31%)