Protein Alignment FAR2 and CG14893

DIOPT Version :10

• Sequence 1: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_650568.2
• Gene: CG14893 / 42023
• FlyBaseID: FBgn0038451
• Length: 510
• Species: Drosophila melanogaster
• Alignment Length: 513
• Identity: 180/513 - (35%)
• Similarity: 277/513 - (53%)
• Gaps: 56/513 - (10%)

Human    24 IAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFEKV 88
            |..||..|.:.:||||||||||::|||.||: ::|.||.::|||.|:.:|:|:.......|||.:
  Fly    16 IQGFYKDKVVFLTGATGFLGKVIIEKLLRTT-EVKRIYAMMRPKRGKDIQERLAIWQKDPLFEVL 79

Human    89 KEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVTATR 153
            .:..|:..::|..|..|....|..|::.|.:.|:|..:|:.|.||||||::.|..|:.:|...||
  Fly    80 LKAKPDALKRIFVIAGDCLDPDLGINRSDRKLLVSEVHIVIHGAATVRFNEPLHVALAINTRGTR 144

Human   154 QLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYP----CPVEPKKIIDSLEWLDDAIIDEITP 214
            .:|.:|.:|.:|||::|||||:|||.:..|:|..||    |  :...::...|.|.:.::|::.|
  Fly   145 LMLQLAKEMLQLEAYLHISTAFSNCVIFRIEEKFYPEHLTC--DANSVLAMSELLSEQMMDKLAP 207

Human   215 KLIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGK 279
            .|:.::||.|||||||.|.||.:|..:|.::|.|||::.||.:||..||:||:.||...|.....
  Fly   208 TLVGNFPNTYTYTKALAEDVVLREFGDLPLSIFRPSVIIATHEEPVSGWIDNLYGPIAHIYGVSH 272

Human   280 GFLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAVHRPKSTLVYHITSGNMNPCNWHKMGVQVLA 344
            |.||.........|.::|||...|..||..|.|:  :.||                .:..:...|
  Fly   273 GVLRLTTYDKDGYASLVPVDYCANAALASIWQTS--KDKS----------------QRNAISQPA 319

Human   345 TFEKIPFERPFRRPNANFTSNS--------FTSQYW----NAVS------------HRAPAIIYD 385
            .:...|.|:.... |.:|..:|        .|...|    :.:|            |..|...||
  Fly   320 IYTLAPSEKNLLL-NTDFIKHSLIHRNDFPLTKMIWYPFVHNISNPRIFPLAAFFYHTLPGYFYD 383

Human   386 CYLRLTGRKPRMTKLMNRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNW 450
            ..|||:|||||:.||...:...:::||:|:|.||.:.|.:|:.|...:||||:|::|||:..|:|
  Fly   384 LALRLSGRKPRLVKLYRSIHANIAVLEHFMNNSWHFETKSTDRLRVMMSPEDRRLYNFDMETLDW 448

Human   451 LEYIENYVLGVKKYLLKE--DMAGIPKAKQRLKRLRNIHYLFNTALFLIA----WRLL 502
            .||....:.|::.||.||  ....:.:.::...||:.:||.|.|.|.:||    |.|:
  Fly   449 KEYFRKALFGMRLYLTKEPPTQESLEQGRRLFYRLKILHYSFVTLLCVIAGFLLWTLV 506

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	117/307 (38%)
		Sterile	377..467	CDD:460779	38/89 (43%)
CG14893	NP_650568.2	FAR-N_SDR_e	23..339	CDD:187547	122/337 (36%)
		Sterile	374..465	CDD:460779	38/90 (42%)