Protein Alignment FAR2 and CG30427

DIOPT Version :10

• Sequence 1: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_726498.1
• Gene: CG30427 / 37986
• FlyBaseID: FBgn0043792
• Length: 506
• Species: Drosophila melanogaster
• Alignment Length: 490
• Identity: 156/490 - (31%)
• Similarity: 279/490 - (56%)
• Gaps: 18/490 - (3%)

Human    21 MSTIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLF 85
            :|.:..:|..|:|.||||:||:||||:|||..:...||.:.|:.|||.|:..:.|:.::....:|
  Fly     5 LSPVQEYYKDKTIFITGASGFMGKVLLEKLLYSCHSLKEVIIICRPKRGKAPETRLEEMFKLPIF 69

Human    86 EKVKEVCPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVT 150
            :::|:..|.:.:::.....|:..:...:|.|.::.:...|||:||.|||::.:..||.|:.:|:.
  Fly    70 QRIKDERPEMLKRVTIYQGDVTFDQLGLSGESLKHVTENTNIVFHMAATLKLEGNLRDAIDMNLL 134

Human   151 ATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPK 215
            .||:.|.:|.:|.:||||||:|||:.||:...:.|.:|..|.:|:.::...||:|...:|.|||.
  Fly   135 GTRRALNVAKEMKQLEAFIHLSTAFCNCDQDVMYEKVYEFPHKPEDLMRLAEWMDVKTLDAITPD 199

Human   216 LIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKG 280
            |::..||.|||:|.|.|::|:....::.:.|.|||||.....||.||||||:|||.|::|..|||
  Fly   200 LLKPHPNTYTYSKRLAELLVRDHYESMPVIIARPSIVTPAVAEPLPGWVDNMNGPTGVLIGAGKG 264

Human   281 FLRAIKATPMAVADVIPVDTVVNLMLAVGWYT--AVHRPKSTLVYHITSGNMNPCNW-------H 336
            .:|::.......::|||||..:|.::.:.::.  |..||....||::|..:.....|       .
  Fly   265 VIRSMICNGELKSEVIPVDIAINGLILLPYHNSLAEKRPLQIPVYNLTVDDAKKRTWKWIMDVGR 329

Human   337 KMGVQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLM 401
            .:|:       |.|||.....|:.|.||:.|.......:....||.:.|..|.:.|::..|.::.
  Fly   330 DLGI-------KYPFEVGLWYPDGNMTSSKFYHTICTILFMWLPAYLIDFLLLIFGQRRFMIRVQ 387

Human   402 NRLLRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLL 466
            .::...:.:|::|..|||::.:.:.|.:..||...|:|:|..:...::..||::..:||.::|::
  Fly   388 TKIAVGLEVLQFFTTRSWDFKSTHFEQIYKELGSTDRRIFKINTDDVDDYEYMKVSILGGRQYVM 452

Human   467 KEDMAGIPKAKQRLKRLRNIHYLFNTALF--LIAW 499
            ||.:..:||::.:|:.:..:..:..|.:.  |:.|
  Fly   453 KEPLTSLPKSRIQLRFMYVLDRICKTMIISGLLYW 487

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	113/305 (37%)
		Sterile	377..467	CDD:460779	22/89 (25%)
CG30427	NP_726498.1	FAR-N_SDR_e	15..321	CDD:187547	113/305 (37%)
		Sterile	362..453	CDD:460779	22/90 (24%)