Protein Alignment FAR2 and CG8306

DIOPT Version :10

• Sequence 1: XP_011519049.1
• Gene: FAR2 / 55711
• HGNCID: 25531
• Length: 535
• Species: Homo sapiens
• Sequence 2: NP_611140.3
• Gene: CG8306 / 36857
• FlyBaseID: FBgn0034142
• Length: 516
• Species: Drosophila melanogaster
• Alignment Length: 509
• Identity: 161/509 - (31%)
• Similarity: 275/509 - (54%)
• Gaps: 14/509 - (2%)

Human    22 STIAAFYGGKSILITGATGFLGKVLMEKLFRTSPDLKVIYILVRPKAGQTLQQRVFQILDSKLFE 86
            |.|..||.|:::.|||||||:|..::|||.|..|::..:|:|:|.|.|:::|:|:.::..:.:|:
  Fly     4 SPITDFYAGRNVFITGATGFVGVTIVEKLLRDVPNVGTLYLLMRAKKGKSVQERLEELKKNSVFD 68

Human    87 KVKEV-CPNVHEKIRAIYADLNQNDFAISKEDMQELLSCTNIIFHCAATVRFDDTLRHAVQLNVT 150
            |.||: ..:...||..|..|:......||.:|.|.|:...|::||.|||:.|..:|:....:|:.
  Fly    69 KFKELQLQSRLSKIVPIEGDVGLEHLGISPKDRQTLIDNVNVVFHSAATLDFFQSLKETTNINLR 133

Human   151 ATRQLLLMASQMPKLEAFIHISTAYSNCNLKHIDEVIYPCPVEPKKIIDSLEWLDDAIIDEITPK 215
            .||:::.:..|:..|:|.:|:|:||.|..|..::|.:||.|.:|:|||...|.|:|..:.|:.||
  Fly   134 GTRRVVELCQQIKNLDALVHVSSAYVNAYLTKVEEKLYPAPEDPEKIIQLSETLNDDALKELEPK 198

Human   216 LIRDWPNIYTYTKALGEMVVQQESRNLNIAIIRPSIVGATWQEPFPGWVDNINGPNGIIIATGKG 280
            |::|.||.||:||.|.|..|...:......|:|||::.|.|:||.|||..:.|||.|..:...||
  Fly   199 LLKDHPNTYTFTKHLAEHEVANVASKFPCGIVRPSMITAAWKEPIPGWTISKNGPQGFFMGASKG 263

Human   281 FLRAIKATPMAVADVIPVDTVVNLMLAVGWYTAV------HRPKSTLVYHITSGNMNPCNWHKMG 339
            .||.:...|..:.|.||:|.|||.::..|:|...      .||....::|:||....|..:..|.
  Fly   264 VLRRLPLDPSIIMDYIPIDVVVNGIITTGYYVNSLQAKNGGRPADLQIFHLTSSTYKPFRFELMT 328

Human   340 VQVLATFEKIPFERPFRRPNANFTSNSFTSQYWNAVSHRAPAIIYDCYLRLTGRKPRMTKLMNRL 404
            .::.:.....|.......||.....:.:..:....:.|..||||.|...::.|.:|.:.:|...:
  Fly   329 DKINSYLHDYPLNSAVWYPNLRLVKSLWVFRLSAILFHFIPAIILDLVTKIGGGRPILVRLHKNV 393

Human   405 LRTVSMLEYFINRSWEWSTYNTEMLMSELSPEDQRVFNFDVRQLNWLEYIENYVLGVKKYLLKED 469
            ..:::.||.||...|.:.:.....|...|:..|::.|..|:.:|.|.||..|.:|||::||.||.
  Fly   394 WNSLNTLEKFIFTEWHFDSKRLLALSKTLNIVDKKKFFIDIGELAWDEYFSNTILGVRQYLSKEP 458

Human   470 MAGIPKAKQRLKRLRNIHYLFNTALFLIAWRLLI-------ARSQMARNVWFFI 516
            :..:.||:::.|.|..:|.....:.:...::|::       |::.:...|.:::
  Fly   459 IKNLEKARRKDKILLGLHVALQLSFWYGVFKLIVCLTGISTAKAALVLPVLYYL 512

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FAR2	XP_011519049.1	FAR-N_SDR_e	31..335	CDD:187547	113/310 (36%)
		Sterile	377..467	CDD:460779	29/89 (33%)
CG8306	NP_611140.3	FAR-N_SDR_e	13..339	CDD:187547	114/325 (35%)
		Sterile	365..456	CDD:460779	29/90 (32%)