Protein Alignment PRKAG1 and Prkag1

DIOPT Version :10

• Sequence 1: NP_001193638.1
• Gene: PRKAG1 / 5571
• HGNCID: 9385
• Length: 340
• Species: Homo sapiens
• Sequence 2: NP_058061.2
• Gene: Prkag1 / 19082
• MGIID: 108411
• Length: 330
• Species: Mus musculus
• Alignment Length: 340
• Identity: 322/340 - (94%)
• Similarity: 329/340 - (96%)
• Gaps: 10/340 - (2%)

Human     1 METVISSDSSPAVENEHPQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALV 65
            ||:| :::||||:||||.|||||||||||||||||||||||||||||||||||||||||||||||
Mouse     1 MESV-AAESSPALENEHFQETPESNNSVYTSFMKSHRCYDLIPTSSKLVVFDTSLQVKKAFFALV 64

Human    66 TNGVRAAPLWDSKKQSFVVLRALSCPLGMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 130
            ||||||||||||||||||         ||||||||||||||||||||||||||||||||||||||
Mouse    65 TNGVRAAPLWDSKKQSFV---------GMLTITDFINILHRYYKSALVQIYELEEHKIETWREVY 120

Human   131 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKP 195
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   121 LQDSFKPLVCISPNASLFDAVSSLIRNKIHRLPVIDPESGNTLYILTHKRILKFLKLFITEFPKP 185

Human   196 EFMSKSLEELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAA 260
            |||||||:|||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   186 EFMSKSLQELQIGTYANIAMVRTTTPVYVALGIFVQHRVSALPVVDEKGRVVDIYSKFDVINLAA 250

Human   261 EKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDENDVVKGIVSLS 325
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||
Mouse   251 EKTYNNLDVSVTKALQHRSHYFEGVLKCYLHETLETIINRLVEAEVHRLVVVDEHDVVKGIVSLS 315

Human   326 DILQALVLTGGEKKP 340
            |||||||||||||||
Mouse   316 DILQALVLTGGEKKP 330

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PRKAG1	NP_001193638.1	CBS_euAMPK_gamma-like_repeat1	38..183	CDD:341388	135/144 (94%)
		CBS repeat	45..127	CDD:341388	72/81 (89%)
		CBS repeat	139..183	CDD:341388	43/43 (100%)
		CBS_euAMPK_gamma-like_repeat2	209..332	CDD:341399	121/122 (99%)
		CBS repeat	210..275	CDD:341399	64/64 (100%)
		CBS repeat	286..329	CDD:341399	41/42 (98%)
Prkag1	NP_058061.2	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21		13/20 (65%)
		CBS_euAMPK_gamma-like_repeat1	37..173	CDD:341388	135/144 (94%)
		CBS repeat	44..117	CDD:341388	72/81 (89%)
		CBS repeat	129..173	CDD:341388	43/43 (100%)
		AMPK pseudosubstrate	137..158		20/20 (100%)
		CBS_euAMPK_gamma-like_repeat2	199..322	CDD:341399	121/122 (99%)
		CBS repeat	200..265	CDD:341399	64/64 (100%)
		CBS repeat	276..319	CDD:341399	41/42 (98%)