Protein Alignment MAP7D1 and ens

DIOPT Version :10

• Sequence 1: NP_060537.3
• Gene: MAP7D1 / 55700
• HGNCID: 25514
• Length: 841
• Species: Homo sapiens
• Sequence 2: NP_001097498.1
• Gene: ens / 38491
• FlyBaseID: FBgn0264693
• Length: 1241
• Species: Drosophila melanogaster
• Alignment Length: 1090
• Identity: 250/1090 - (22%)
• Similarity: 377/1090 - (34%)
• Gaps: 432/1090 - (39%)

Human    70 SPSGQVGPRPAPPQEESPSSEAKSRGPTPPAMGPRDARPPRRSSQPSPTAV---------PASDS 125
            |..||.|.....|:.|:.:...:||..:  |.....|..|.:.|..|..|.         ..|.|
  Fly     3 SLGGQHGNISTNPEVENTAKRPESREGS--AERKAHAFAPAKISGCSAGATLHWFAQVGGQISAS 65

Human   126 PPTKQEVKKAGERHKLAKERR-EERAKYLAAKKAVWLEKEEKAKALREKQLQERRRRLEEQRLKA 189
            ....|..|...|:.|.|::|: |||.:.:...:|    :.|.|:..||::.:|||||:||.|.:.
  Fly    66 EDDSQASKDREEKLKYARDRQNEERHRKIEELRA----QAEAAQRYREQKEEERRRRIEEIRTRD 126

Human   190 EQRRAALEERQRQKLEKNKERYEAAIQRS-VKKTWAEIRQQ-RWSWAGALHHSSP---------- 242
            .::|..:|||::...|..|||.|..:::: .:::..|:::: |.|...|...|:|
  Fly   127 TEKRHQVEERKKAIFEAEKERREYILKKNQERESRIEVKKRDRNSIGFAFGSSTPRLLDVPADYG 191

Human   243 --------GHKTSGSRCSVSAVNLPKH------VDSIINKRLSKS----------SATLW----- 278
                    |.:.|.|..:|:..:|.:.      .||...||.|.|          |::::
  Fly   192 LVSPSAFWGQRRSTSISNVAGASLTRRSSERELADSGAKKRASSSTDRQDDHRRKSSSMYEVFNW 256

Human   279 ----NSPSRNRSLQLSAWESSI------------------------------------------- 296
                :.|.:..||.::..|.:|
  Fly   257 GYSNDEPPKRFSLSIAGSEINIDGPANPHPPPTSKQTANAHRPTNLTTTTATSTTTAGHNNFNNN 321

Human   297 -----VDRLMTPTLSFLARSRSAVTL------PRNGRDQGRG---CDPGRGPTWGRA-------- 339
                 .|.:.:..:.|.:..|....|      ||:|....||   ..|.|.|  |||
  Fly   322 NSYRKEDSVDSSPMVFRSVYRRKTDLMPTIPSPRDGHYGSRGSLSSTPARTP--GRAYSMNRLDQ 384

Human   340 ------------------------------GASLARGPQPDRTHPSAAVPVCPRSASASPLTPCS 374
                                          .|||..|........||.......:.|.|......
  Fly   385 LAQPIRRNGEHMRAILERERRERELEMLDETASLGGGGGRRGAGSSARARRAGSAGSGSSSAAGI 449

Human   375 VTRSVHRCAPAGERGERRKPNAGGSPAPVRRRPEASPVQKKEKKDKERENEKEKSALARERSLKK 439
            ::||:...|..|.:.||.|.:.||. .....||.||..  ..::|...::..:.|:.:...|...
  Fly   450 MSRSMTHLAGGGGQRERGKYSLGGG-ISTSFRPLASGA--GGQRDSTSKSMTQISSWSVYGSTAP 511

Human   440 RQSLP---------------ASPRARLSASTAS-------------------------------- 457
            :|..|               |:.:..|.:|.||
  Fly   512 QQPPPNHLHHLRQSTLGLQTAATKKYLQSSFASASSFNSASFRANATGRGRQQQYAISTNPHRFL 576

Human   458 ELSPKS---------------------------KARPSSP-------STSWHRPASPCPSP---- 484
            :|.|.|                           .:||.|.       |||...|..|..:|
  Fly   577 DLDPNSLLLMNSASLLVNAGSRSGNATPGGHFNNSRPGSAMSTSTNMSTSGLVPRRPATAPRKPR 641

Human   485 -----GPGHTL--------PPKPPSPRGTTASPKGRVRRKEEA--------------------KE 516
                 |.|.:|        ..||| .:.|.|||..:...|..|                    |:
  Fly   642 PASIAGTGMSLEEINKLKRDQKPP-VKTTAASPSAQTTPKRTANLMSTSLIVTSSSSRLSSAEKK 705

Human   517 SPSAAGP-------EDKSQSKRRASNE-----------KESAAP--------------ASPAPSP 549
            :||...|       ..|:...|.||:|           |:::|.              ..|||:|
  Fly   706 TPSKREPPVPKAASASKALPSRTASSERISRLTKEPKTKDTSAMTRSMIVTSSSTSTITKPAPAP 770

Human   550 -APSPTPAPPQ----KE---------QPPAETPTDA----------------------------- 571
             ||:..|.|.|    ||         .|.||.||:|
  Fly   771 VAPTSAPVPEQNGVAKEVEKTTADEPVPEAEVPTEAPVVVPSVSKAEKEALNTEKTEEGARQEEE 835

Human   572 ----------AVLTS-----------------PPAPAPPVTPSK-----------PMAGT----- 593
                      |::||                 |...|.|..||:           |..|.
  Fly   836 QILAVESVPEALVTSINVEEKSDEGNEKEVPKPQEQAAPKKPSRSKENSEVRELTPPEGADLMTA 900

Human   594 -------TDREEATRLLAEKRRQAREQRERE-EQER-RLQAER------------DKRMREEQLA 637
                   |..|||...|||:||.|||:.||: |.|| ||:|||            .:|:.||:..
  Fly   901 SMMAKKITTEEEAKAALAERRRLAREEAERQAELERQRLEAERLAEIKAQEEEAERQRLFEEEST 965

Human   638 R--EAEARAERE------AEARRREEQEAREKAQAEQEEQERLQKQKEEAEARSREEAERQRLER 694
            |  |.:.|.|.|      .||::|||:|.|.:   |:||::|:  ::||||.:::||||:||:|.
  Fly   966 RLAEEQRRGEEERLRKAIEEAQQREEEEKRRR---EEEEKQRV--EREEAEKKAKEEAEKQRVEV 1025

Human   695 EKHFQQQEQERQERRKRLEEIMKRTRKSEVSETKQKQDSKEANANGSSPE 744
            .:..:::|:||:|||||:|.||.||||...:.|..|..:.:|....::||
  Fly  1026 AERLKREEKEREERRKRVEAIMLRTRKGGAATTPSKDANDKAAPAATAPE 1075

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
MAP7D1	NP_060537.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..151		25/90 (28%)
		PRK12323	<2..>131	CDD:481241	16/69 (23%)
		PTZ00121	<130..>221	CDD:173412	31/92 (34%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	184..208		7/23 (30%)
		PHA03247	<315..595	CDD:223021	105/569 (18%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	316..813		177/741 (24%)
		MAP7	588..726	CDD:461709	69/182 (38%)
ens	NP_001097498.1	PTZ00121	<70..>166	CDD:173412	32/99 (32%)
		PRK07003	<627..>820	CDD:235906	43/193 (22%)
		PTZ00121	<786..>966	CDD:173412	43/179 (24%)