Protein Alignment RADIL and MYO4

DIOPT Version :10

• Sequence 1: NP_060529.4
• Gene: RADIL / 55698
• HGNCID: 22226
• Length: 1075
• Species: Homo sapiens
• Sequence 2: NP_009373.1
• Gene: MYO4 / 851204
• SGDID: S000000027
• Length: 1471
• Species: Saccharomyces cerevisiae
• Alignment Length: 308
• Identity: 62/308 - (20%)
• Similarity: 122/308 - (39%)
• Gaps: 61/308 - (19%)

Human   507 LFWMSNSIELLYFIQQKCPLYMQSMEEQLDITGSKESLFSCTLTASE-EAMAVLEEVVLYAFQQC 570
            :||:||...|..|...:..||..:..::      |:.|....|...| |.:.|.:::......:.
Yeast  1187 IFWLSNLSRLPAFAANQKTLYEANGGDE------KDKLTLIYLNDLENETLKVFDKIYSTWLVKF 1245

Human   571 VYYVSKSLYICLPALLECPPFQTERRESWSSAPELPEELRRVVSVYQAALDLLRQLQVHPEVASQ 635
            :.:.|..:.| ...:|....|:....|.::.......|...|:..:| .:|     .:|.::.:.
Yeast  1246 MKHASAHIEI-FDMVLNEKLFKNSGDEKFAKLFTFLNEFDAVLCKFQ-VVD-----SMHTKIFND 1303

Human   636 MLAYLFFFSGTLLLNQLLDRGPSLSCFHWPRGVQACARLQQLLEWMRSAGFGAAGEHFFQKL-SC 699
            .|.||    ..:|.|.|:.:.|:|   :|..|.:....:::|:.|            |..:: ..
Yeast  1304 TLKYL----NVMLFNDLITKCPAL---NWKYGYEVDRNIERLVSW------------FEPRIEDV 1349

Human   700 TLNLLATPRA-QLIQMSWTAL---RAAFP---ALSPAQLHRLLTHYQLASAMGPMSTWEPGAQDS 757
            ..||:...:| :::|:..:.|   :..|.   ||:|||:..:|..|:      |.:..|.|..:
Yeast  1350 RPNLIQIIQAVKILQLKISNLNEFKLLFDFWYALNPAQIQAILLKYK------PANKGEAGVPN- 1407

Human   758 PEAFRSEDVLESYEN---PPPIVLPSDGFQVDLEANCLDDSIYQHLLY 802
                   ::|....|   ...:.||.   ::::..:...||...||.|
Yeast  1408 -------EILNYLANVIKRENLSLPG---KMEIMLSAQFDSAKNHLRY 1445

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RADIL	NP_060529.4	RA_Radil_like	50..161	CDD:340636
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	183..237
		FHA_RADIL	244..358	CDD:438785
		Myo5p-like_CBD_Rasip1	414..779	CDD:271256	55/283 (19%)
		PRK07764	<812..956	CDD:236090
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	872..967
		PDZ_Radil-like	972..1059	CDD:467177
MYO4	NP_009373.1	COG5022	2..1471	CDD:227355	62/308 (20%)