Protein Alignment KDM4D and kdm4b

DIOPT Version :10

• Sequence 1: NP_060509.2
• Gene: KDM4D / 55693
• HGNCID: 25498
• Length: 523
• Species: Homo sapiens
• Sequence 2: NP_001076274.2
• Gene: kdm4b / 556504
• ZFINID: ZDB-GENE-060503-664
• Length: 1134
• Species: Danio rerio
• Alignment Length: 376
• Identity: 249/376 - (66%)
• Similarity: 302/376 - (80%)
• Gaps: 11/376 - (2%)

Human    11 AQNPNCN---IMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKEWKARETYDNISEILIA 72
            |..|..|   ||.|.||.|||.||.|||||||:||||.|||||:|||||||.|.:|:.|.:::|.
Zfish    85 APPPGANFNKIMTFRPTMEEFKDFGKYIAYMETQGAHVAGLAKVIPPKEWKPRRSYETIEDMVIP 149

Human    73 TPLQQVASGRAGVFTQYHKKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERKYWKNRIYNSPIYG 137
            .|:.||.:|::|:||||:.:||:|||||||.|||||||.||.|::|:|||||||||..:.|||||
Zfish   150 APIMQVVTGQSGLFTQYNIQKKSMTVGEYRKLANSKKYNTPQHKDFDDLERKYWKNLTFVSPIYG 214

Human   138 ADISGSLFDENTKQWNLGHLGTIQDLLEKECGVVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSIN 202
            |||||||:|.:..:||:|||.|:.|::|:|||:||||||||||||||||||||||||||||||||
Zfish   215 ADISGSLYDPDISEWNIGHLNTLLDMVEQECGIVIEGVNTPYLYFGMWKTTFAWHTEDMDLYSIN 279

Human   203 YLHLGEPKTWYVVPPEHGQRLERLARELFPGSSRGCGAFLRHKVALISPTVLKENGIPFNRITQE 267
            |||.|:||:||.:|||||:||||||:..|||||:||.||||||:.||||::||:..|||:|||||
Zfish   280 YLHFGKPKSWYAIPPEHGKRLERLAQGFFPGSSQGCDAFLRHKMTLISPSILKKYSIPFDRITQE 344

Human   268 AGEFMVTFPYGYHAGFNHGFNCAEAINFATPRWIDYGKMASQCSCGEARVTFSMDAFVRILQPER 332
            .||||:||||||||||||||||||:.||||.|||||||||:||:|.:..|..|||.|||.|||||
Zfish   345 EGEFMITFPYGYHAGFNHGFNCAESTNFATLRWIDYGKMAAQCTCRKDMVKISMDVFVRRLQPER 409

Human   333 YDLWKRGQDRAVVDHMEPRVPASQELS-------TQKEVQLPRRAALGLRQ 376
            |..||:|:|..|:||::|...:|.||.       |.:|..| |||...::|
Zfish   410 YTQWKQGKDTMVLDHLKPTSLSSPELEHWRKNRVTFREKVL-RRAQAKMKQ 459

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KDM4D	NP_060509.2	JmjN	18..58	CDD:128818	31/39 (79%)
		JmjC	179..295	CDD:396791	92/115 (80%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	407..523
kdm4b	NP_001076274.2	None