Protein Alignment KDM4D and jmj3

DIOPT Version :10

• Sequence 1: NP_060509.2
• Gene: KDM4D / 55693
• HGNCID: 25498
• Length: 523
• Species: Homo sapiens
• Sequence 2: NP_595639.1
• Gene: jmj3 / 2540780
• PomBaseID: SPBC83.07
• Length: 752
• Species: Schizosaccharomyces pombe
• Alignment Length: 321
• Identity: 80/321 - (24%)
• Similarity: 126/321 - (39%)
• Gaps: 73/321 - (22%)

Human    18 IMIFHPTKEEFNDFDKYIAYMESQGAHRAGLAKIIPPKE----WKARETYDNISEILIATPLQQV 78
            |.:..|...||.|.:.:|..:|..| .:.|..|::.|..    |  .|.....|::.:...|:::
pombe    34 IPVVEPKISEFVDMESFIRRVERLG-KKYGAIKVVRPSSVLNPW--NEDTMKPSDVKMDLWLERM 95

Human    79 ASGRAGVFTQYH----------KKKKAMTVGEYRHLANSKKYQTPPHQNFEDLERK----YWKNR 129
            .. |.|.:.:..          ||...|.|.: |..:|:..     ..:||:...|    ||::.
pombe    96 VR-RKGEYFEIQSDIDHGSAGPKKPTDMNVDD-RFPSNAGS-----SNDFENNVAKAIAYYWRSL 153

Human   130 IYNSPIYG------------ADISGSLFD-----ENT--KQW-NLGHLGTIQDLLEKECGVVIEG 174
            .::|..||            ..||.:..|     .||  ..| |:||
pombe   154 THDSLWYGYTNRPSIPFYFIPSISAAQKDRVHLRSNTLINTWPNVGH------------------ 200

Human   175 VNTPYLYFGMWKTTFAWHTEDMDLYSINYLHL-GEPKTWYVVPPEHGQRLERLARELFPGSSRGC 238
                 |:.|.||||..|..|..:|:::. :|| |....|||:|..|.:..::||.:|.......|
pombe   201 -----LFAGKWKTTLPWRVESPELHAVQ-VHLGGSSLQWYVIPSAHSESFKKLAGKLAQDEHWRC 259

Human   239 GAFLRHKVALISPTVLKENGIPFNRITQEAGEFMVTFPYGYHAGFNHGFNCAEAINFATPR 299
            ..||.|:..|..|:.|.:|||.......:..|.::|||..:|:.|..|........|.:||
pombe   260 SDFLLHQNILFPPSTLVQNGIVTYSTVLKQDELLITFPGTHHSAFCLGDAVLRRFVFRSPR 320

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KDM4D	NP_060509.2	JmjN	18..58	CDD:128818	11/43 (26%)
		JmjC	179..295	CDD:396791	37/116 (32%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	407..523
jmj3	NP_595639.1	JmjN	33..74	CDD:128818	11/40 (28%)
		JmjC	200..316	CDD:396791	38/139 (27%)