Protein Alignment YEATS2 and TAF14

DIOPT Version :10

• Sequence 1: NP_001338299.1
• Gene: YEATS2 / 55689
• HGNCID: 25489
• Length: 1423
• Species: Homo sapiens
• Sequence 2: NP_015196.1
• Gene: TAF14 / 855974
• SGDID: S000006050
• Length: 244
• Species: Saccharomyces cerevisiae
• Alignment Length: 199
• Identity: 46/199 - (23%)
• Similarity: 81/199 - (40%)
• Gaps: 37/199 - (18%)

Human   206 VKKTIVVGNVSKYIPPDKREENDQSTHKWMVYV-----RGSRREPSINHFVKKVWFFLHPSY-KP 264
            ||:||.: ...::|.|:.....:....:|.:.:     .|.....:|   ..||.:.|||:: .|
Yeast     5 VKRTIRI-KTQQHILPEVPPVENFPVRQWSIEIVLLDDEGKEIPATI---FDKVIYHLHPTFANP 65

Human   265 NDLVEVREPPFHLTRRGWGEFPVRVQVHFKDSQNKRIDIIHNLK-LDRTYTGLQTLGAETVVDVE 328
            |.  ...:|||.:..:|||.||:.:.|...:...:| .|.|:|. |..:|.      .|.|:.:.
Yeast    66 NR--TFTDPPFRIEEQGWGGFPLDISVFLLEKAGER-KIPHDLNFLQESYE------VEHVIQIP 121

Human   329 LHRHSLGEDCIYPQSSESDISDA-----------PPSLPLTIPAPVKASSPIKQSHEPVPDTSVE 382
            |::..|.|:.....|:|...::.           ..:.|....|...::|.:|.|      ..:|
Yeast   122 LNKPLLTEELAKSGSTEETTANTGTIGKRRTTTNTTAEPKAKRAKTGSASTVKGS------VDLE 180

Human   383 KAGF 386
            |..|
Yeast   181 KLAF 184

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
YEATS2	NP_001338299.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	117..198
		YEATS_YEATS2_like	208..331	CDD:341126	32/129 (25%)
		Histone H3K27cr binding. /evidence=ECO:0000269|PubMed:27103431, ECO:0007744|PDB:5IQL	259..261		1/1 (100%)
		Histone H3K27cr binding. /evidence=ECO:0000269|PubMed:27103431, ECO:0007744|PDB:5IQL	282..284		1/1 (100%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	466..487
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	514..541
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	795..843
		DUF5585	<869..>1119	CDD:465521
TAF14	NP_015196.1	TFG3	2..242	CDD:227366	46/199 (23%)