Protein Alignment SLC30A6 and ZnT35C

DIOPT Version :10

• Sequence 1: NP_001180442.1
• Gene: SLC30A6 / 55676
• HGNCID: 19305
• Length: 501
• Species: Homo sapiens
• Sequence 2: NP_609741.3
• Gene: ZnT35C / 34890
• FlyBaseID: FBgn0028516
• Length: 472
• Species: Drosophila melanogaster
• Alignment Length: 348
• Identity: 62/348 - (17%)
• Similarity: 124/348 - (35%)
• Gaps: 90/348 - (25%)

Human   110 LSNSL----------------MTCLISYWVTLRKPSPVYSFGFERLEVLAVFASTVLAQLGALFI 158
            |||||                |..|.:.|:..|..:...|||:.|.||:...||..:..:....:
  Fly   111 LSNSLAIATDAAHLLTDFASFMISLFAIWIAGRPSTQRMSFGWYRAEVIGAMASVFMIWVITGIL 175

Human   159 LKESAERFLE-QPEIHTGRLLVGTFVALCFNLFTMLSIR-----------------NKPFAYVSE 205
            :..:..|.:. ..|::...:|:.:.:|:..|:...:.::                 :|..::| :
  Fly   176 VWLAIGRLISGDYEVNAKIMLITSGLAILVNVIMGVQLQHGHSHGLGGGHGHSHGGSKNASHV-Q 239

Human   206 AASTSWLQEHVADLSRSLC----------GIIPGLSSIFLPRMNPFVLIDLAGAFA--------- 251
            |.||.........:...:.          |.:|..|......::|.:.:::|...|
  Fly   240 ATSTPCSDSPSQRIEGGVAYAPEDAELPGGGLPTFSYQNTKLVDPTLDLEIAAVLAETAPGSHHH 304

Human   252 ----------LCITYMLIEI--------------------NNYFAVDTASAIAIALMTFGTMYPM 286
                      :.:...||.:                    ..|..||.......:::...|.:.:
  Fly   305 GGPVGREAVNMNVRAALIHVIGDVIQSVGVFVAAGVIYFWPEYSIVDPICTFVFSIIVLFTTFTI 369

Human   287 SVYSGKVLLQTTPPHVIGQLDKLIREVSTLDGVLEVRNEHFWTLGFGSLAGSVHVRIRRDANEQM 351
            ...:..||::.||.::  ...::::....::||..|.|...|.|....:|.|.|:.|..:||.:.
  Fly   370 MKDALLVLMEGTPNYM--HYAEVLQIFQGIEGVERVHNLRIWALSINKVALSAHLAIAENANPKR 432

Human   352 VLAHVTNRL---YTLVSTLTVQI 371
            :|...|:.:   |....| |:||
  Fly   433 ILDAATSAVHLRYNFFET-TIQI 454

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SLC30A6	NP_001180442.1	CzcD	113..371	CDD:440843	57/343 (17%)
ZnT35C	NP_609741.3	CzcD	73..455	CDD:440843	62/348 (18%)