Protein Alignment OSGEP and Tcs3

DIOPT Version :10

• Sequence 1: NP_060277.1
• Gene: OSGEP / 55644
• HGNCID: 18028
• Length: 335
• Species: Homo sapiens
• Sequence 2: NP_648880.1
• Gene: Tcs3 / 39811
• FlyBaseID: FBgn0283681
• Length: 347
• Species: Drosophila melanogaster
• Alignment Length: 346
• Identity: 242/346 - (69%)
• Similarity: 279/346 - (80%)
• Gaps: 11/346 - (3%)

Human     1 MPAVLGFEGSANKIGVGVVRDGKVLANPRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTESG 65
            |...||.||||||||:|::||||||||.||||:||||.||||.:||:|||..||.|::.:|.|:.
  Fly     1 MVCALGIEGSANKIGIGIIRDGKVLANVRRTYITPPGEGFLPKETAKHHREAILGLVESSLKEAQ 65

Human    66 LTSQDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGATSPTVLY 130
            |.|.|:|.|.|||||||..||:..|:||||::.|||.||:||||||||||||||||||.:|||||
  Fly    66 LKSSDLDVICYTKGPGMAPPLLVGAIVARTLSLLWNIPLLGVNHCIGHIEMGRLITGAQNPTVLY 130

Human   131 VSGGNTQVIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDPSPGYNIEQMAKRGKKLVELPY 195
            ||||||||||||..||||||||||||||||||||||::|:||||||||||||:||...:.::|||
  Fly   131 VSGGNTQVIAYSNKRYRIFGETIDIAVGNCLDRFARIIKLSNDPSPGYNIEQLAKSSNRYIKLPY 195

Human   196 TVKGMDVSFSGILSFIEDVAH-----------RMLATGECTPEDLCFSLQETVFAMLVEITERAM 249
            .|||||||||||||:|||:|.           :.......:..|||:|||||:||||||||||||
  Fly   196 VVKGMDVSFSGILSYIEDLAEPGKRQNKRKKPQEEEVNNYSQADLCYSLQETIFAMLVEITERAM 260

Human   250 AHCGSQEALIVGGVGCNVRLQEMMATMCQERGARLFATDERFCIDNGAMIAQAGWEMFRAGHRTP 314
            |||||.|.|||||||||.||||||..||:|||.:|||||||:|||||.|||.||.||||:|.|.|
  Fly   261 AHCGSNEVLIVGGVGCNERLQEMMRIMCEERGGKLFATDERYCIDNGLMIAHAGAEMFRSGTRMP 325

Human   315 LSDSGVTQRYRTDEVEVTWRD 335
            ..:|.||||:|||||.|:|||
  Fly   326 FEESYVTQRFRTDEVLVSWRD 346

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OSGEP	NP_060277.1	ASKHA_NBD_OSGEP_like_euk	4..310	CDD:466982	224/316 (71%)
Tcs3	NP_648880.1	ASKHA_NBD_OSGEP_like_euk	3..321	CDD:466982	224/317 (71%)