Protein Alignment OSGEP and Tcs4

DIOPT Version :10

• Sequence 1: NP_060277.1
• Gene: OSGEP / 55644
• HGNCID: 18028
• Length: 335
• Species: Homo sapiens
• Sequence 2: NP_608347.1
• Gene: Tcs4 / 32982
• FlyBaseID: FBgn0031060
• Length: 409
• Species: Drosophila melanogaster
• Alignment Length: 370
• Identity: 105/370 - (28%)
• Similarity: 154/370 - (41%)
• Gaps: 57/370 - (15%)

Human     4 VLGFEGSANKIGVGVV-RDGKVLAN---PRRTYVTPPGTGFLPGDTARHHRAVILDLLQEALTES 64
            |||.|.|.:..|:.:| ..|:|:||   .::.:.|..| |.:|......|||.|....|..:..:
  Fly    27 VLGIETSCDDTGIAIVDTTGRVIANVLESQQEFHTRYG-GIIPPRAQDLHRARIESAYQRCMEAA 90

Human    65 GLTSQDIDCIAYTKGPGMGAPLVSVAVVARTVAQLWNKPLVGVNHCIGHIEMGRLITGATSP--- 126
            .|....:..||.|..||:...|:.....||.:|:...|||:.|:|...|....|:    ..|
  Fly    91 QLKPDQLTAIAVTTRPGLPLSLLVGVRFARHLARRLQKPLLPVHHMEAHALQARM----EHPEQI 151

Human   127 ----TVLYVSGGNTQ-VIAYSEHRYRIFGETIDIAVGNCLDRFARVLKISNDP-----SPGYNIE 181
                ..|..|||:.| |:|....|..:.|:|:|.|.|...|:..|.|::...|     :.|..||
  Fly   152 GYPFLCLLASGGHCQLVVANGPGRLTLLGQTLDDAPGEAFDKIGRRLRLHILPEYRLWNGGRAIE 216

Human   182 QMAKRGKK--LVELPYTV---KGMDVSFSGIL--SFIEDVAHRMLATGECTPE--------DLCF 231
            ..|:....  ..|.|..:   :..:.||:||.  ||   .|.|.....|.||.        |.|.
  Fly   217 HAAQLASDPLAYEFPLPLAQQRNCNFSFAGIKNNSF---RAIRARERAERTPPDGVISNYGDFCA 278

Human   232 SLQETVFAMLVEITERAMAHC--------GSQEALIV--GGVGCNVRLQEMMATMCQERGARLFA 286
            .|..:|...|:..|:||:.:|        |.....:|  |||..|..:...:..:..:.|.|.|.
  Fly   279 GLLRSVSRHLMHRTQRAIEYCLLPHRQLFGDTPPTLVMSGGVANNDAIYANIEHLAAQYGCRSFR 343

Human   287 TDERFCIDNGAMIAQAGWEMFRAGHRTPLSDSGVTQRYRTDEVEV 331
            ..:|:|.|||.|||..|.|..       |.|...:.||..|.:::
  Fly   344 PSKRYCSDNGVMIAWHGVEQL-------LQDKEASTRYDYDSIDI 381

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
OSGEP	NP_060277.1	ASKHA_NBD_OSGEP_like_euk	4..310	CDD:466982	100/347 (29%)
Tcs4	NP_608347.1	ASKHA_NBD_OSGEPL1_QRI7_euk	27..366	CDD:466984	100/353 (28%)