DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC39A4 and Zip102B

DIOPT Version :9

Sequence 1:	NP_570901.3	Gene:	SLC39A4 / 55630	HGNCID:	17129	Length:	647	Species:	Homo sapiens
Sequence 2:	NP_001284713.1	Gene:	Zip102B / 43786	FlyBaseID:	FBgn0039902	Length:	297	Species:	Drosophila melanogaster

Alignment Length:	128	Identity:	42/128 - (32%)
Similarity:	62/128 - (48%)	Gaps:	27/128 - (21%)

- Green bases have known domain annotations that are detailed below.

Human   500 ITLGDAVHNFADGLAVGAAFASSWK-TGLATSLAVFCHELPHELGDFAALLHAGL---SVRQALL 560
            :|||..||..|||:|:|||..:|.: ..:...||:..|:.|...|....|||..:   .:|:.|:
  Fly   119 LTLGLVVHAAADGVALGAAATTSHQDVEIIVFLAIMLHKAPAAFGLVTFLLHEKVDRHQIRRHLV 183

Human   561 LNLASA-----LTAFAGLYVALAVGVSEESEAWILAV-ATGL--------FLYVALCDMLPAM 609
            |...||     ||.|         |:.:|.:..:.:| |||:        |||||...:||.:
  Fly   184 LFSLSAPLMTILTYF---------GIGQEQKDTLNSVNATGIAMLFSAGTFLYVATVHVLPEL 237

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC39A4	NP_570901.3	ZIP4_domain	46..196	CDD:375719
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	236..255
		Zip	328..638	CDD:308248	42/128 (33%)
		Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	458..486
Zip102B	NP_001284713.1	Zip	18..235	CDD:294300	40/124 (32%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910