DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment ZDHHC7 and CG4956

DIOPT Version :9

Sequence 1:	NP_001139020.1	Gene:	ZDHHC7 / 55625	HGNCID:	18459	Length:	345	Species:	Homo sapiens
Sequence 2:	NP_651428.2	Gene:	CG4956 / 43114	FlyBaseID:	FBgn0039370	Length:	302	Species:	Drosophila melanogaster

Alignment Length:	170	Identity:	50/170 - (29%)
Similarity:	75/170 - (44%)	Gaps:	34/170 - (20%)

- Green bases have known domain annotations that are detailed below.

Human   141 LLGAVPKGNATKEYMESLQLK-----PGE--VIYKCPKCCCIKPERAHHCSICKRCIRKMDHHCP 198
            :||....|..|...::||.|:     .||  :.:.|..|..:.|.|:.|||:|..||.|.||||.
  Fly    90 ILGNWWLGCMTNTSVDSLVLERQYPVAGEAHLWHYCSTCQKLVPPRSWHCSLCNICILKRDHHCT 154

Human   199 WVNNCVGEKNQRFFVLFTMYIALSSVHALILCG------------------FQFISCVRGQWTEC 245
            :..:|:|.||||:|:.|..:::..|..||:..|                  ||       ..|:.
  Fly   155 FFASCIGHKNQRYFLAFLFHLSFGSGQALVYNGILNWTNKAFLVVDPLLLMFQ-------DTTQD 212

Human   246 SDFSPPITV--ILLIFLCLEGLLFFTFTAVMFGTQIHSIC 283
            :||....|:  :..:.|.|.|:..|.|...|.....:|.|
  Fly   213 ADFKWKYTIANLFKLNLFLFGVPLFMFVFQMIMVYRNSTC 252

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
ZDHHC7	NP_001139020.1	zf-DHHC	168..295	CDD:307600	41/136 (30%)
CG4956	NP_651428.2	zf-DHHC	123..251	CDD:279823	39/134 (29%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_COG5273
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810