DRSC/TRiP Functional Genomics Resources

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Protein Alignment ZDHHC7 and GABPI

DIOPT Version :9

Sequence 1:NP_001139020.1 Gene:ZDHHC7 / 55625 HGNCID:18459 Length:345 Species:Homo sapiens
Sequence 2:NP_608741.1 Gene:GABPI / 33516 FlyBaseID:FBgn0031495 Length:420 Species:Drosophila melanogaster


Alignment Length:305 Identity:65/305 - (21%)
Similarity:118/305 - (38%) Gaps:83/305 - (27%)


- Green bases have known domain annotations that are detailed below.


Human    53 MTWL------LVAYADFVVTFVMLLPSKDFWYSVVNGVIFNCLAVLALSSHLRTMLTDPEKSSDC 111
            ::||      ::...:|.|..:.|.|.::  |::   :.|:|.|:..|.|           :...
  Fly   151 LSWLVFSVFYMIIIFEFQVPLLELAPEEN--YAL---MFFSCAALYCLYS-----------AKAL 199

Human   112 RP-SACTVKTGLDP--TLVGIC----GEGTESVQSLLLGAVPKGNATKEYMES-LQLKPGEV--- 165
            .| :..:.:.|..|  .|.||.    ||.....|:.|            .||| |.|...||   
  Fly   200 SPLNLVSAQYGTTPKDELPGIAEASSGEEQAEAQTTL------------QMESVLSLDDDEVGDM 252

Human   166 --------IYKCPKCC--C--IKPERAHHCSICKRCIRKMDHHCPWVNNCVGEKNQRFFVLFTMY 218
                    ::..|..|  |  :.|.||:||.:|..|:::.|||..|:|.|:||:|   :|.:.:.
  Fly   253 DTAERSGLMHGQPNICEICRKVTPRRAYHCPVCGTCVKRRDHHSYWLNCCIGERN---YVWYIVG 314

Human   219 IALSSVHALI--------LC---------GFQFISCVRGQWTECSDFSPPITVILLIFLCLEGLL 266
            :|||.:..|:        :|         |:..:..     .:||:......:.:...:....||
  Fly   315 LALSEIALLLGANLTLTSICHPFMVVRPLGYPVLLP-----DDCSEVFEGFDLGISFVVACYALL 374

Human   267 FFTFTAVMFGTQIHSICNDETEIERLKSEKPTWERRLRWEGMKSV 311
            ..::.|.:...|.:......|..|..::.......|: |...:::
  Fly   375 ISSYIAFILARQAYLWWKGSTLHEYKRTSNAAGRNRI-WSNWRAI 418

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
ZDHHC7NP_001139020.1 zf-DHHC 168..295 CDD:307600 34/147 (23%)
GABPINP_608741.1 zf-DHHC 262..399 CDD:279823 33/144 (23%)


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 1 0.900 - - E1_COG5273
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
Isobase 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
User_Submission 00.000 Not matched by this tool.
21.810

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