Sequence 1: | NP_001365368.1 | Gene: | KIF21A / 55605 | HGNCID: | 19349 | Length: | 1675 | Species: | Homo sapiens |
---|---|---|---|---|---|---|---|---|---|
Sequence 2: | NP_009490.1 | Gene: | KIP1 / 852216 | SGDID: | S000000159 | Length: | 1111 | Species: | Saccharomyces cerevisiae |
Alignment Length: | 1292 | Identity: | 312/1292 - (24%) |
---|---|---|---|
Similarity: | 521/1292 - (40%) | Gaps: | 364/1292 - (28%) |
- Green bases have known domain annotations that are detailed below.
Human 4 APDESSVRVAVRIRPQLAKEKIEGCHICTS----------VTPGEPQVFLGKDKAFTFDYVFDID 58
Human 59 SQQEQIYIQCIEKLIEGCFEGYNATVFAYGQTGAGKTYTMGTGFDVNI-----------VEEELG 112
Human 113 IISRAVKHLFKSIEEKKHIAIKNGLPAPDFKVNAQFLELYNEEVLDLFDTTRDID--AKSKKSNI 175
Human 176 RI--HEDSTGGIYTVGVTTRTVNTESEMMQCLKLGALSRTTASTQMNVQSSRSHAIFTIHVCQTR 238
Human 239 VCPQIDADNATDNKIISESAQMNEFETLTAKFHFVDLAGSERLKRTGATGERAKEGISINCGLLA 303
Human 304 LGNVISALGDKSKRATHVPYRDSKLTRLLQDSLGGNSQTIMIACVSPSDRDFMETLNTLKYANRA 368
Human 369 RNIKNKVMVNQDRAS--------QQINALRSE-----------ITRLQMELMEYKTGKRIIDEEG 414
Human 415 VESINDMFHENAMLQTENNNLRVRIKAMQETVDALRSRITQLVSDQANHVLARAGEGNEEISNMI 479
Human 480 HSYIKEIEDLRAKLLESEAVNENLRKNLTRATARAPYFSGSSTFSPTILSSDKETIEIIDLAKKD 544
Human 545 LEKLKRKEKRKKKRL--QKLEESNREERSVAGKEDNTDTDQEKKEEKGVSERENNELEVEESQEV 607
Human 608 SDHEDEEEEEEEEEDDIDGGESSDESDSESDEKANYQA---DLANITCEIAIKQ--KLI------ 661
Human 662 ------DELENSQKRLQTLKKQYEEKLMMLQHKIRDTQLERDQVLQNLGS--VESYSEEKAKKVR 718
Human 719 SEYEKKLQAMNKELQRLQAAQKEHARLLKNQSQYEKQLKKLQQDVMEMKKTKVRLMKQMKEE--- 780
Human 781 -QEKARLTES----RRNREIAQLKKDQRKRDHQLRLLEAQKRNQE--VVLRRKTEEVTALRRQVR 838
Human 839 PMSDKVAGKVTRKLSSSDAPAQDTGSSAAAVETDASRTGAQQKMRIPVARVQALP---------- 893
Human 894 ----------TPATN---GNRKKYQRKGLTGRVFISKTARMKWQLLERRVTDIIMQKMTISNMEA 945
Human 946 DMNRLLKQREELTKRREKLSKRREKIVKENGEGDKNVANINEEMESLTANIDYINDSISDCQANI 1010
Human 1011 MQMEEAKEEGETLDVTAVINACTLTEARYLL--DHFLSMGINKGL-QAAQKEAQ-IKVLE--GRL 1069
Human 1070 KQTEITSATQNQLLFHMLKEKAELNPELDALLGHALQDLDSVPLENVEDST-----DEDAP---- 1125
Human 1126 ---LNS---------PGSEGSTLSSDLMKLCGEVKPKNKARRRTTTQMELLYADSSE 1170 |
Gene | Sequence | Domain | Region | External ID | Identity |
---|---|---|---|---|---|
KIF21A | NP_001365368.1 | KISc_KIF4 | 8..372 | CDD:276823 | 141/388 (36%) |
Cast | <364..836 | CDD:401982 | 104/521 (20%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 556..641 | 12/86 (14%) | |||
Smc | <644..1004 | CDD:224117 | 73/411 (18%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 779..804 | 9/32 (28%) | |||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 841..881 | 5/39 (13%) | |||
Rcc_KIF21A | 936..1017 | CDD:410204 | 17/80 (21%) | ||
Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite | 1116..1138 | 8/42 (19%) | |||
Interaction with KANK1 and KANK2. /evidence=ECO:0000269|PubMed:29183992 | 1146..1167 | 6/20 (30%) | |||
WD40 | 1340..1653 | CDD:238121 | |||
WD 1 | 1346..1383 | ||||
WD 2 | 1386..1424 | ||||
WD40 repeat | 1391..1450 | CDD:293791 | |||
WD 3 | 1450..1488 | ||||
WD40 repeat | 1456..1491 | CDD:293791 | |||
WD 4 | 1491..1533 | ||||
WD40 repeat | 1496..1540 | CDD:293791 | |||
WD 5 | 1542..1579 | ||||
WD40 repeat | 1548..1581 | CDD:293791 | |||
WD 6 | 1583..1622 | ||||
WD40 repeat | 1588..1624 | CDD:293791 | |||
WD 7 | 1625..1662 | ||||
KIP1 | NP_009490.1 | KISc_BimC_Eg5 | 50..419 | CDD:276815 | 146/397 (37%) |
235kDa-fam | <423..>948 | CDD:130673 | 126/706 (18%) | ||
Blue background indicates that the domain is not in the aligned region. |
Tool | Simple Score | Weighted Score | Original Tool Information | |||
---|---|---|---|---|---|---|
BLAST Result | Score | Score Type | Cluster ID | |||
Compara | 0 | 0.000 | Not matched by this tool. | |||
Domainoid | 0 | 0.000 | Not matched by this tool. | |||
eggNOG | 0 | 0.000 | Not matched by this tool. | |||
Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
Homologene | 0 | 0.000 | Not matched by this tool. | |||
Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
Isobase | 0 | 0.000 | Not matched by this tool. | |||
OMA | 0 | 0.000 | Not matched by this tool. | |||
OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
Panther | 0 | 0.000 | Not matched by this tool. | |||
Phylome | 1 | 0.910 | - | - | ||
RoundUp | 0 | 0.000 | Not matched by this tool. | |||
SonicParanoid | 0 | 0.000 | Not matched by this tool. | |||
SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
TreeFam | 0 | 0.000 | Not matched by this tool. | |||
1 | 0.910 |