Protein Alignment PARL and parla

DIOPT Version :10

• Sequence 1: XP_005247639.1
• Gene: PARL / 55486
• HGNCID: 18253
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_001014320.1
• Gene: parla / 541485
• ZFINID: ZDB-GENE-050327-8
• Length: 383
• Species: Danio rerio
• Alignment Length: 387
• Identity: 195/387 - (50%)
• Similarity: 249/387 - (64%)
• Gaps: 61/387 - (15%)

Human     1 MAWRGWAQRGWGCGQAWGA--SVGGRS-CEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEP 62
            ||||       .|...|..  |:...| |.:.|           |.|...||:|||||..|..|.
Zfish     1 MAWR-------SCFMKWTQINSINASSLCPKST-----------RLNIHPQQRCGFRKTERPSES 47

Human    63 RRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIR---SLIKPLFFTVGFTGCAFGSAAIWQYESL 124
            ::....|..||...:..:||..     ..|.|.|   .|.:||.||||||||:||:|||.||||:
Zfish    48 KKGVQETEAEAGGHNRAVPPKP-----VPPLPPRRPHQLFRPLVFTVGFTGCSFGAAAILQYESV 107

Human   125 KSRVQSYFDGIKADWLDSIRPQKEG--------------DFRKE-------INKWWNNLSDGQRT 168
            |||||...:..|.:..|::   .||              :|:|:       ::.:|:.||:||:|
Zfish   108 KSRVQLAIEEAKEEKRDTL---LEGHDTTYWHNWWNQLSNFQKQVILLISAVDDFWSGLSEGQKT 169

Human   169 VTGIIAANVLVFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFS 233
            ||||||.|.:|.|.||||::||.:::|||||||||..|.||:||:|||:|:.||..||||||:||
Zfish   170 VTGIIALNTVVLCCWRVPAMQRFLVKYFTSNPASKTRCLPMVLSSFSHYSVIHMVVNMYVLWTFS 234

Human   234 SSIVNILGQEQFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAI 298
            ||||::||:|||:|:|||.||||.|||||.|.||||.||||||||:||||||||||||||.:|.|
Zfish   235 SSIVSLLGREQFLALYLSGGVISTFVSYVFKTATGRLGPSLGASGSIMTVLAAVCTKIPEAKLGI 299

Human   299 IFLPMFTFTAGNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGL 360
            :.||:.:|:|||||||::|:|.||::|||:||||||||||||||:     |.:.   .||.|
Zfish   300 VLLPVISFSAGNALKALVALDIAGLVLGWRFFDHAAHLGGALFGV-----WYIG---YGHEL 353

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARL	XP_005247639.1	Rhomboid	209..350	CDD:426384	99/140 (71%)
parla	NP_001014320.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	35..75		13/44 (30%)
		Rhomboid	210..351	CDD:426384	100/148 (68%)