Protein Alignment PARL and Parl

DIOPT Version :10

• Sequence 1: XP_005247639.1
• Gene: PARL / 55486
• HGNCID: 18253
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_001005767.1
• Gene: Parl / 381038
• MGIID: 1277152
• Length: 377
• Species: Mus musculus
• Alignment Length: 360
• Identity: 311/360 - (86%)
• Similarity: 327/360 - (90%)
• Gaps: 10/360 - (2%)

Human     1 MAWRGWAQRGWGCGQAWGASVGGRSCEELTAVLTPPQLLGRRFNFFIQQKCGFRKAPRKVEPRRS 65
            ||.:||.||||.||.||...:|| ...||:|. ..|:|||||||.|:||||||||||||||||||
Mouse     1 MALQGWVQRGWRCGPAWAPPLGG-GYRELSAT-QAPRLLGRRFNLFVQQKCGFRKAPRKVEPRRS 63

Human    66 DPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFTGCAFGSAAIWQYESLKSRVQS 130
            |.|:|||||||||||||:|||||||||||||:|:||.|||:||||||||||||||||||||||||
Mouse    64 DTGSSGEAYKRSALIPPLEETVFYPSPYPIRTLVKPFFFTIGFTGCAFGSAAIWQYESLKSRVQS 128

Human   131 YFDGIKADWLDSIRPQKEGDFRKEINKWWNNLSDGQRTVTGIIAANVLVFCLWRVPSLQRTMIRY 195
            |||||||||||||||||||:.|||||||||:|||||||||||||||.||||||||||||||||||
Mouse   129 YFDGIKADWLDSIRPQKEGNLRKEINKWWNSLSDGQRTVTGIIAANALVFCLWRVPSLQRTMIRY 193

Human   196 FTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFMAVYLSAGVISNFVS 260
            ||||||||||||||||||||||||||||||||||||||||||||||||||:||||||||||||||
Mouse   194 FTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQEQFVAVYLSAGVISNFVS 258

Human   261 YVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTAGNALKAIIAMDTAGMIL 325
            ||.|||||||||||||||||||||||||||||||||||||||:||||||||||||||||||||||
Mouse   259 YVCKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPVFTFTAGNALKAIIAMDTAGMIL 323

Human   326 GWKFFDHAAHLGGALFGMISLYTWRLACCLLGHGL 360
            |||||||||||||||||:     |.:.   .||.|
Mouse   324 GWKFFDHAAHLGGALFGI-----WYIT---YGHEL 350

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARL	XP_005247639.1	Rhomboid	209..350	CDD:426384	131/140 (94%)
Parl	NP_001005767.1	Rhomboid	207..348	CDD:426384	132/148 (89%)