Protein Alignment PARL and rho-7

DIOPT Version :10

• Sequence 1: XP_005247639.1
• Gene: PARL / 55486
• HGNCID: 18253
• Length: 394
• Species: Homo sapiens
• Sequence 2: NP_523704.1
• Gene: rho-7 / 36281
• FlyBaseID: FBgn0033672
• Length: 351
• Species: Drosophila melanogaster
• Alignment Length: 295
• Identity: 130/295 - (44%)
• Similarity: 191/295 - (64%)
• Gaps: 24/295 - (8%)

Human    54 RKAPRKVEPRRSDPGTSGEAYKRSALIPPVEETVFYPSPYPIRSLIKPLFFTVGFT-GCAFGSAA 117
            ||....::|...:|..:.:                 .:|.|:.::||.:.||..|| || |..|.
  Fly    47 RKQSSNLKPTTGEPAAAEQ-----------------NTPVPVNNVIKAVAFTGAFTVGC-FAGAT 93

Human   118 IWQYESLKSRVQSYFDGIKADWLDSIRPQKEGDF----RKEINKWWNNLSDGQRTVTGIIAANVL 178
            |.:||:.:|.:.......:..|..| |...:.|:    :::|.:.|::|:.|.:....|:..|::
  Fly    94 ILEYENTRSLILEKARQARFGWWQS-RSLADRDYWTQIKQDIRRHWDSLTPGDKMFAPILLCNLV 157

Human   179 VFCLWRVPSLQRTMIRYFTSNPASKVLCSPMLLSTFSHFSLFHMAANMYVLWSFSSSIVNILGQE 243
            .|.:||||:|:.|||.|||||||:||:|.||.||||||:|..|:.|||||:.||:::....||:|
  Fly   158 AFAMWRVPALKSTMITYFTSNPAAKVVCWPMFLSTFSHYSAMHLFANMYVMHSFANAAAVSLGKE 222

Human   244 QFMAVYLSAGVISNFVSYVGKVATGRYGPSLGASGAIMTVLAAVCTKIPEGRLAIIFLPMFTFTA 308
            ||:||||||||.|:.:|.:.|.||.:.|.||||||||||:||.|||:.|:.:|:|:|||..||:|
  Fly   223 QFLAVYLSAGVFSSLMSVLYKAATSQAGMSLGASGAIMTLLAYVCTQYPDTQLSILFLPALTFSA 287

Human   309 GNALKAIIAMDTAGMILGWKFFDHAAHLGGALFGM 343
            |..:|.::.:|.||:::||||||||||||||:||:
  Fly   288 GAGIKVLMGIDFAGVVMGWKFFDHAAHLGGAMFGI 322

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PARL	XP_005247639.1	Rhomboid	209..350	CDD:426384	80/135 (59%)
rho-7	NP_523704.1	Rhomboid	186..327	CDD:426384	81/137 (59%)