DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment SIRPG and beat-IV

DIOPT Version :9

Sequence 1:	NP_061026.2	Gene:	SIRPG / 55423	HGNCID:	15757	Length:	387	Species:	Homo sapiens
Sequence 2:	NP_001262876.1	Gene:	beat-IV / 42778	FlyBaseID:	FBgn0039089	Length:	446	Species:	Drosophila melanogaster

Alignment Length:	217	Identity:	43/217 - (19%)
Similarity:	82/217 - (37%)	Gaps:	42/217 - (19%)

- Green bases have known domain annotations that are detailed below.

Human   180 LKWFKNGNELSDF-------QTNVDPTGQSVAYSIRSTARVVLDPWDVRSQVI--CEVA-----H 230
            :||:|:..|...:       :|:....|..|...:...:||:|....:.|..:  |||:     .
  Fly   214 IKWYKDNEEFYRYVPKARPPKTSYRVDGVRVIEELSDASRVLLRGLTLNSTGLYRCEVSAEAPNF 278

Human   231 VTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQRE 295
            .::||:   |..::....|..|.:...|...::|..:.:.|...|.:|.| .|.|..|
  Fly   279 SSVQGE---GRMDIVFLPRDGPHIRGQQYQYQIGEYLYLNCTSGKSHPAS-HLQWFVN------- 332

Human   296 TASTLTENKDGTYNWTSWFLVNISDQRDDVVLTCQVK--------HDGQLAVSKRLALEVTVHQ- 351
            ....|.|:....||       :|..:...:..|..::        |:|.:.|....::...:.:
  Fly   333 EQPILDEHYLHKYN-------DIVHKHGLITSTLGLQLPLEPRHFHEGDMRVKCLASISPVLWKG 390

Human   352 -KDQSSDATPGPASSLTALLLI 372
             |:......||...:..|:||:
  Fly   391 GKESVLQRRPGIIDNREAMLLV 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SIRPG	NP_061026.2	IgV_SIRP	33..143	CDD:319346
		IgC_SIRP_domain_2	145..248	CDD:319314	17/81 (21%)
		IgC_SIRP_domain_3	250..353	CDD:319334	19/112 (17%)
beat-IV	NP_001262876.1	Ig	<212..285	CDD:299845	16/73 (22%)
beat-IV	NP_001262876.1	Ig	314..>362	CDD:299845	13/62 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910