DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SIRPG and beat-Va

DIOPT Version :9

Sequence 1:	NP_061026.2	Gene:	SIRPG / 55423	HGNCID:	15757	Length:	387	Species:	Homo sapiens
Sequence 2:	NP_001189214.1	Gene:	beat-Va / 41578	FlyBaseID:	FBgn0038087	Length:	300	Species:	Drosophila melanogaster

Alignment Length:	265	Identity:	55/265 - (20%)
Similarity:	90/265 - (33%)	Gaps:	64/265 - (24%)

- Green bases have known domain annotations that are detailed below.

Human   164 VSFTCESHGFSPRDITL---KWFKNGNEL-------SDFQTNVDPTGQSVA----YSIRSTARVV 214
            |:.:|   .:..|..||   ||:|:..|.       |......|..|..|.    ....|:.|:.
  Fly    40 VTLSC---SYDMRGHTLNSVKWYKDHEEFFRYSPLTSPIYMTFDVAGLQVLEGKYVCNESSCRLD 101

Human   215 LDPWDVRSQVI--CEVAHVTLQGD----PLRGTANLSEAIRVP---PTLEVTQQPMRVGNQVNVT 270
            |.....:|..:  |||:     ||    .|...|:......:|   |.:|......|:...:..|
  Fly   102 LSLQGAKSTGLYKCEVS-----GDAPHFKLADKADNMTVAALPQNDPLIESFNSMYRMEEYLKAT 161

Human   271 CQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNW--------TSWFLVNISDQR----- 322
            | :..|.....:|||..||...........|:.....:::        ..:||   ..||
  Fly   162 C-ISDFSSLPTRLTWYINGEQPLLGELYPTTDTSLAAHDYVLRRQRLQVQFFL---QGQRFFQAG 222

Human   323 DDVVLTCQVKHDGQLAVSKRLALEVTVHQKD--------QSSDATPGPA--------SSLTALLL 371
            ..:.|.|..:.:....:.:...|..::.|.|        :.::|..|.|        :||.:..|
  Fly   223 KILELKCVAEIENYPELRREKTLSASLSQYDNFNNQMPLRHANANSGSAQRSILCGRTSLISAFL 287

Human   372 IAVLL 376
            .|:||
  Fly   288 AAILL 292

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SIRPG	NP_061026.2	IgV_SIRP	33..143	CDD:319346
		IgC_SIRP_domain_2	145..248	CDD:319314	24/103 (23%)
		IgC_SIRP_domain_3	250..353	CDD:319334	21/118 (18%)
beat-Va	NP_001189214.1	None
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910