DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SIRPG and beat-Ia

DIOPT Version :9

Sequence 1:	NP_061026.2	Gene:	SIRPG / 55423	HGNCID:	15757	Length:	387	Species:	Homo sapiens
Sequence 2:	NP_001285975.1	Gene:	beat-Ia / 34947	FlyBaseID:	FBgn0013433	Length:	437	Species:	Drosophila melanogaster

Alignment Length:	200	Identity:	45/200 - (22%)
Similarity:	75/200 - (37%)	Gaps:	35/200 - (17%)

- Green bases have known domain annotations that are detailed below.

Human   179 TLKWFKNGNELSDFQTNVDP-------TGQSVAYSIRSTARVVLDPWDVRS--QVICEVAHVTLQ 234
            ::||:|...|...:.....|       .|..|.....:.::||||...:.:  :..|||:.....
  Fly    59 SVKWYKGRREFYRYTPKETPPMKVFHFPGVKVRRVSSNESQVVLDAVTMATSGKYSCEVSADAPS 123

Human   235 GDPLRGTANLSEAIRVP---PTLEVTQQPMRVGNQVNVTCQVRKFYPQSLQLTWSENGNVCQ--- 293
            ...|...|.| |.|..|   |.:...:...|||:.:...|..|...| :..|||:.|.....
  Fly   124 FHTLIAAAEL-EVIETPHNAPFITGIRPRYRVGDILRGNCTSRHSRP-AANLTWTVNNEEVNPAL 186

Human   294 -------RETASTLTENKDGTYNWTSWFLVNISDQRDD---VVLTCQVK-HDGQLAVSKRLALEV 347
                   |:..:.:.....|.:     |:|  :||..|   :.|.|..: ||.....::::.||.
  Fly   187 VRHHKILRDARNDMETAVVGIH-----FVV--TDQHFDNGKLKLRCSAQLHDVYWKTTEKIILET 244

Human   348 TVHQK 352
            .:..|
  Fly   245 DLFPK 249

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SIRPG	NP_061026.2	IgV_SIRP	33..143	CDD:319346
		IgC_SIRP_domain_2	145..248	CDD:319314	18/77 (23%)
		IgC_SIRP_domain_3	250..353	CDD:319334	25/119 (21%)
beat-Ia	NP_001285975.1	Ig	32..118	CDD:299845	13/58 (22%)
beat-Ia	NP_001285975.1	Ig	161..240	CDD:299845	18/86 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	1	0.910