Protein Alignment SIRPG and Sirpb1c

DIOPT Version :9

• Sequence 1: NP_061026.2
• Gene: SIRPG / 55423
• HGNCID: 15757
• Length: 387
• Species: Homo sapiens
• Sequence 2: NP_001166930.1
• Gene: Sirpb1c / 100038947
• MGIID: 3807521
• Length: 391
• Species: Mus musculus
• Alignment Length: 391
• Identity: 218/391 - (55%)
• Similarity: 279/391 - (71%)
• Gaps: 18/391 - (4%)

Human     6 SWPHPPGPFLLLTLLLGLTEVAGEEELQMIQPEKLLLVTVGKTATLHCTVTSLLPVGPVLWFRGV 70
            :|.|.|...|||.||||| :.|...||::|||.|...|..|.:|||:|||||||||||:.||:||
Mouse     6 AWTHIPHCVLLLILLLGL-KGAAMRELKVIQPVKSFFVGAGGSATLNCTVTSLLPVGPIRWFKGV 69

Human    71 GPGRELIYNQKEGHFPRVTTVSDLTKRNNMDFSIRISSITPADVGTYYCVKFRKGSPE-NVEFKS 134
            |..|.|||:.....|||:|.|||:|||:|:|||||||::||||.||||||||::|..| ::|.:|
Mouse    70 GQSRLLIYSFTGERFPRITNVSDVTKRSNLDFSIRISNVTPADSGTYYCVKFQRGPSEPDMEIQS 134

Human   135 GPGTEMALGAKPSAPVVLGPAARTTPEHTVSFTCESHGFSPRDITLKWFKNGNELSDFQTNVDPT 199
            |.|||:::.||||:|:|.|||||..|:.||:|||.||||.||::||||||||||:|..:|:|:|.
Mouse   135 GGGTELSVFAKPSSPMVSGPAARAVPQQTVAFTCRSHGFFPRNLTLKWFKNGNEISHLETSVEPE 199

Human   200 GQSVAYSIRSTARVVLDPWDVRSQVICEVAHVTLQGDPLRGTANLSEAIRVPPTLEVTQQPMRVG 264
            ..||:|.:.||.:|||:|.|||||:||||.||||...||||.|::||.|:||||||::|||..|.
Mouse   200 ETSVSYRVSSTVQVVLEPRDVRSQIICEVDHVTLDRAPLRGIAHISEFIQVPPTLEISQQPTMVW 264

Human   265 NQVNVTCQVRKFYPQSLQLTWSENGNVCQRETASTLTENKDGTYNWTSWFLVNISDQRDDVVLTC 329
            |.:.||||::||||...|:||.||||:.:||...||..||||||||.|..|||||...:::|:||
Mouse   265 NVIIVTCQIQKFYPPRFQVTWLENGNISRREVPFTLIVNKDGTYNWISCLLVNISALEENMVVTC 329

Human   330 QVKHDGQLAVSKRLALEVTVHQKDQSSDATPGPASSLTALLLIAVLLGP----------IYVPWK 384
            ||:||||..|.:...:.||.||:.:.. .|.|     .|.:.:|||||.          ||:..|
Mouse   330 QVEHDGQAEVIETHTVVVTEHQRVKEL-KTAG-----IAKIPVAVLLGSKILLLIAATVIYMRKK 388

Human   385 Q 385
            |
Mouse   389 Q 389

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
SIRPG	NP_061026.2	IgV_SIRP	33..143	CDD:319346	67/110 (61%)
		IgC_SIRP_domain_2	145..248	CDD:319314	65/102 (64%)
		IgC_SIRP_domain_3	250..353	CDD:319334	58/102 (57%)
Sirpb1c	NP_001166930.1	IG_like	42..119	CDD:214653	51/76 (67%)
		V-set	45..142	CDD:284989	62/96 (65%)
		Ig	141..252	CDD:299845	68/110 (62%)
		IgC	247..341	CDD:143166	55/93 (59%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83971949
Domainoid	1	1.000	146	1.000	Domainoid score	I34754
eggNOG	1	0.900	-	-		E1_2BRY5
HGNC	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	449	1.000	Inparanoid score	I12964
Isobase	0	0.000	Not matched by this tool.
NCBI	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG36121
OrthoDB	1	1.010	-	-		D114611at9347
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR19971
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X1115
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
	11	10.870