Protein Alignment NPY4R and npy4r

DIOPT Version :10

• Sequence 1: NP_005963.4
• Gene: NPY4R / 5540
• HGNCID: 9329
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_571515.1
• Gene: npy4r / 30717
• ZFINID: ZDB-GENE-980526-393
• Length: 377
• Species: Danio rerio
• Alignment Length: 358
• Identity: 173/358 - (48%)
• Similarity: 244/358 - (68%)
• Gaps: 31/358 - (8%)

Human    34 CQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQPLT 98
            |..|..:.:.:|..|.:..::|:|||:.|:|:.:.|::..|||::|||||:.||.|:.:.|.|.|
Zfish    35 CWQSSTMTLTLVLCYCLVLILGLLGNILLICIIMHQRDPPNVTSILIANLSVSDILVSVFCLPFT 99

Human    99 AVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIVLI 163
            .|||:||:||||..||::..|:||:|||||:|||||:||||||||::|:|||||:.|||:.::.:
Zfish   100 VVYTLMDHWIFGALLCRLMPFVQCVSVTVSVLSLVLIALERHQLILHPSGWKPSVPQAYIAVLTV 164

Human   164 WVIACVLSLPFLANSILENVFHKNHSKALEF----LADKVVCTESWPLAHHRTIYTTFLLLFQYC 224
            |::|||.||||||       ||...|:....    |:...||.|.||...|:..|||.|||||||
Zfish   165 WLLACVTSLPFLA-------FHLLTSEPYSLFPAPLSQLQVCLEVWPSQDHKLAYTTSLLLFQYC 222

Human   225 LPLGFILVCYARIYRCLQRQGRVF-----------HKGTYSLRAGHMKQVNVVLVVMVVAFAVLW 278
            .||..:|:||.||:..|||:.|:.           |:     |..|.|::||:|..:|.||||.|
Zfish   223 CPLLLMLLCYLRIFLRLQRRERMLERQCSRNREDEHR-----RVMHSKRINVMLATLVAAFAVCW 282

Human   279 LPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTCQQS 343
            |||:.||.:.|...|.:|:|:.||:|.:||||||:||||||.||||||:||:|::.::||.| ..
Zfish   283 LPLNAFNVVADCDQEVLPVCNHNLLFSLCHLLAMSSTCVNPIIYGFLNSNFRKDVASVVLHC-HF 346

Human   344 APLEES-EHLPLSTVHTEVSKGSLRLSGRSNPI 375
            .|||:| ||.|:||::|:||:.|.||  |:|.:
Zfish   347 QPLEDSYEHFPMSTMNTDVSRTSFRL--RNNSV 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY4R	NP_005963.4	7tmA_NPY4R	42..333	CDD:320519	151/305 (50%)
		TM helix 1	43..69	CDD:320519	8/25 (32%)
		TM helix 2	76..101	CDD:320519	12/24 (50%)
		TM helix 3	114..144	CDD:320519	21/29 (72%)
		TM helix 4	155..176	CDD:320519	11/20 (55%)
		TM helix 5	211..240	CDD:320519	17/28 (61%)
		TM helix 6	258..288	CDD:320519	16/29 (55%)
		TM helix 7	301..326	CDD:320519	19/24 (79%)
npy4r	NP_571515.1	7tm_GPCRs	43..337	CDD:475119	151/305 (50%)
		TM helix 1	45..69	CDD:320519	8/23 (35%)
		TM helix 2	78..100	CDD:320519	10/21 (48%)
		TM helix 3	116..138	CDD:320519	13/21 (62%)
		TM helix 4	159..175	CDD:320519	6/15 (40%)
		TM helix 5	210..233	CDD:320519	14/22 (64%)
		TM helix 6	268..290	CDD:320519	13/21 (62%)
		TM helix 7	305..330	CDD:320519	19/24 (79%)