Protein Alignment NPY4R and Npy4r

DIOPT Version :10

• Sequence 1: NP_005963.4
• Gene: NPY4R / 5540
• HGNCID: 9329
• Length: 375
• Species: Homo sapiens
• Sequence 2: NP_113769.1
• Gene: Npy4r / 29471
• RGDID: 61864
• Length: 375
• Species: Rattus norvegicus
• Alignment Length: 373
• Identity: 278/373 - (74%)
• Similarity: 313/373 - (83%)
• Gaps: 0/373 - (0%)

Human     1 MNTSHLLALLLPKSPQGENRSKPLGTPYNFSEHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCV 65
            ||||||:|.|.|...||:|.:..|.:.||.|:.||||.|::.||:|:||:|||:||||||||:.|
  Rat     1 MNTSHLMASLSPAFLQGKNGTNSLDSLYNLSDGCQDSADLLAFIITTYSVETVLGVLGNLCLIFV 65

Human    66 TVRQKEKANVTNLLIANLAFSDFLMCLLCQPLTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSIL 130
            |.|||||:|||||||||||||||||||:|||||..|||||||||||.||||..||||||||||||
  Rat    66 TTRQKEKSNVTNLLIANLAFSDFLMCLICQPLTVTYTIMDYWIFGEVLCKMLTFIQCMSVTVSIL 130

Human   131 SLVLVALERHQLIINPTGWKPSISQAYLGIVLIWVIACVLSLPFLANSILENVFHKNHSKALEFL 195
            |||||||||||||||||||||||||||||||:||.|:|.|||||||||||.::||.||||.:|||
  Rat   131 SLVLVALERHQLIINPTGWKPSISQAYLGIVVIWFISCFLSLPFLANSILNDLFHYNHSKVVEFL 195

Human   196 ADKVVCTESWPLAHHRTIYTTFLLLFQYCLPLGFILVCYARIYRCLQRQGRVFHKGTYSLRAGHM 260
            .|||||..||...|||.||||||||||||:||.||||||.|||:.||||.|.||..|.|.|.|.|
  Rat   196 EDKVVCFVSWSSDHHRLIYTTFLLLFQYCVPLAFILVCYMRIYQRLQRQRRAFHTHTCSSRVGQM 260

Human   261 KQVNVVLVVMVVAFAVLWLPLHVFNSLEDWHHEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFL 325
            |::|.:|:.||.|||||||||||||:||||:.||||.||||||||:|||.|||||||||||||||
  Rat   261 KRINGMLMAMVTAFAVLWLPLHVFNTLEDWYQEAIPACHGNLIFLMCHLFAMASTCVNPFIYGFL 325

Human   326 NTNFKKEIKALVLTCQQSAPLEESEHLPLSTVHTEVSKGSLRLSGRSN 373
            |.||||:||||||||:...|..|.|.||||||||::||||:|:..:||
  Rat   326 NINFKKDIKALVLTCRCRPPQGEPEPLPLSTVHTDLSKGSMRMGSKSN 373

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY4R	NP_005963.4	7tmA_NPY4R	42..333	CDD:320519	231/290 (80%)
		TM helix 1	43..69	CDD:320519	18/25 (72%)
		TM helix 2	76..101	CDD:320519	22/24 (92%)
		TM helix 3	114..144	CDD:320519	27/29 (93%)
		TM helix 4	155..176	CDD:320519	16/20 (80%)
		TM helix 5	211..240	CDD:320519	24/28 (86%)
		TM helix 6	258..288	CDD:320519	20/29 (69%)
		TM helix 7	301..326	CDD:320519	22/24 (92%)
Npy4r	NP_113769.1	7tmA_NPY4R	43..333	CDD:320519	231/289 (80%)
		TM helix 1	43..69	CDD:320519	18/25 (72%)
		TM helix 2	76..101	CDD:320519	22/24 (92%)
		TM helix 3	114..144	CDD:320519	27/29 (93%)
		TM helix 4	155..176	CDD:320519	16/20 (80%)
		TM helix 5	211..240	CDD:320519	24/28 (86%)
		TM helix 6	258..288	CDD:320519	20/29 (69%)
		TM helix 7	301..326	CDD:320519	22/24 (92%)