Protein Alignment NPY4R and XB996286

DIOPT Version :10

• Sequence 1: NP_005963.4
• Gene: NPY4R / 5540
• HGNCID: 9329
• Length: 375
• Species: Homo sapiens
• Sequence 2: XP_017951279.1
• Gene: XB996286 / 100491805
• XenbaseID: XB-GENE-996287
• Length: 376
• Species: Xenopus tropicalis
• Alignment Length: 339
• Identity: 177/339 - (52%)
• Similarity: 235/339 - (69%)
• Gaps: 10/339 - (2%)

Human    32 EHCQDSVDVMVFIVTSYSIETVVGVLGNLCLMCVTVRQKEKANVTNLLIANLAFSDFLMCLLCQP 96
            :.|....|:..|:.|:||:.|::|:|||:.||.|..||||:.|||::|||||||||.|:|..|.|
 Frog    23 QKCGQHPDMTPFLGTAYSLVTILGLLGNISLMYVICRQKERGNVTHILIANLAFSDVLVCAFCLP 87

Human    97 LTAVYTIMDYWIFGETLCKMSAFIQCMSVTVSILSLVLVALERHQLIINPTGWKPSISQAYLGIV 161
            .|||||:||||:||.:|||::.|:||.|||||:|.|||:|.||:|||::|||||||:.|||..::
 Frog    88 FTAVYTVMDYWVFGLSLCKITNFLQCASVTVSVLILVLIAFERYQLILHPTGWKPSVLQAYAAVL 152

Human   162 LIWVIACVLSLPFLANSILENVFHKNHSKALEFLADKVVCTESWPLAHHRTIYTTFLLLFQYCLP 226
            |:||||.:|:.|..::.:|.:..:||.||.:.|||||.||.|||........||..|.|.||.:|
 Frog   153 LVWVIASLLAFPLASSMVLTDTPNKNISKVIGFLADKSVCVESWSSNQQLVAYTISLQLLQYIVP 217

Human   227 LGFILVCYARIYRCLQRQGRVFHKGTYSLRAGHMKQVNVVLVVMVVAFAVLWLPLHVFNSLEDWH 291
            |.|||.||.||...|:.:|.:|.:..     .||::||::.|:||.||||.|||.|:||.:.|||
 Frog   218 LCFILGCYLRISVHLKHRGAMFGRND-----NHMRRVNLMFVIMVGAFAVCWLPFHIFNIIVDWH 277

Human   292 HEAIPICHGNLIFLVCHLLAMASTCVNPFIYGFLNTNFKKEIKALVLTC-----QQSAPLEESEH 351
            |:.||:|:.||||.:||||||.||||||.|||.||:|.|:|:||||..|     ...:.:||.|.
 Frog   278 HQLIPVCYHNLIFSLCHLLAMISTCVNPVIYGLLNSNVKREVKALVQNCTGRKLDTRSAVEEPER 342

Human   352 LPLSTVHTEVSKGS 365
            .|||...:....||
 Frog   343 YPLSLKQSATLPGS 356

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
NPY4R	NP_005963.4	7tmA_NPY4R	42..333	CDD:320519	161/290 (56%)
		TM helix 1	43..69	CDD:320519	12/25 (48%)
		TM helix 2	76..101	CDD:320519	16/24 (67%)
		TM helix 3	114..144	CDD:320519	19/29 (66%)
		TM helix 4	155..176	CDD:320519	10/20 (50%)
		TM helix 5	211..240	CDD:320519	15/28 (54%)
		TM helix 6	258..288	CDD:320519	17/29 (59%)
		TM helix 7	301..326	CDD:320519	19/24 (79%)
XB996286	XP_017951279.1	7tm_GPCRs	34..319	CDD:475119	161/289 (56%)
		TM helix 1	35..59	CDD:320519	11/23 (48%)
		TM helix 2	68..90	CDD:320519	13/21 (62%)
		TM helix 3	106..128	CDD:320519	13/21 (62%)
		TM helix 4	149..165	CDD:320519	6/15 (40%)
		TM helix 5	203..226	CDD:320519	12/22 (55%)
		TM helix 6	250..272	CDD:320519	13/21 (62%)
		TM helix 7	287..312	CDD:320519	19/24 (79%)