DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf130 and Rnf130

DIOPT Version :9

Sequence 1:	XP_009289393.1	Gene:	rnf130 / 553950	ZFINID:	ZDB-GENE-050522-525	Length:	428	Species:	Danio rerio
Sequence 2:	XP_038942740.1	Gene:	Rnf130 / 652955	RGDID:	1562041	Length:	439	Species:	Rattus norvegicus

Alignment Length:	425	Identity:	277/425 - (65%)
Similarity:	335/425 - (78%)	Gaps:	16/425 - (3%)

- Green bases have known domain annotations that are detailed below.

Zfish     6 AAPASCSSCLLALLLAFVSPRCSL-SIGADKTMVNKEDYYSAIVNATVLD-HKGNPQQMVTKND- 67
            |.||..::  ||||      .||| ...||..   .::||:|::|.||.: .:|.|  :..:.|
  Rat     7 AGPARLAA--LALL------TCSLWPTRADNA---SQEYYTALINVTVQEPGRGTP--LTFRIDR 58

Zfish    68 GRYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTRFIVPPKTTHWVAIMQRGKCTFKEKILKAA 132
            ||||.:|||.|.:|.|:||..::|..|..||.|.|||.|||....|:|::|||.|||||||.:||
  Rat    59 GRYGLDSPKAEVRGQVLAPLPIHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAA 123

Zfish   133 AFNASAVIIYNNNTKEDTVTMAHEGTGDIVAVMITESFGKEILGFLEKNQTVLVSVIVGSRGMPK 197
            ..||.||:||||.:||:.|||.|.|||||:||||||..||:||.:||||.:|.:::.||:|..||
  Rat   124 FHNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPK 188

Zfish   198 NINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRG 262
            |.:|||||||||||||||||||||||||||||||.|:||||:|||||||||||||||||||||:|
  Rat   189 NFSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKG 253

Zfish   263 DKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNILKALGVMPNL 327
            ||||:|||:|||||||.|:.|||||:|||||||||.||||||:|||||||||||||||||::|||
  Rat   254 DKETDPDFDHCAVCIESYKQNDVVRVLPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNL 318

Zfish   328 PCVDNMAFDMDRMSRSQTSSQRTALVDLSSETSISLEPLRHSSSSQLPSDEELIPRSGEINIAVT 392
            ||.||:||||:|::|:|..::|:||.||::::|:.|||||.|..|.||.|.||.||:||||||||
  Rat   319 PCTDNVAFDMERLTRTQAVNRRSALGDLANDSSLGLEPLRTSGISPLPQDGELTPRTGEINIAVT 383

Zfish   393 KEWFIVASFGVLSALTLCYMIIRATASTTNYEPML 427
            |||||:||||:||||||||||||||||....|..|
  Rat   384 KEWFIIASFGLLSALTLCYMIIRATASLNANEKYL 418

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf130	XP_009289393.1	PA_GRAIL_like	49..188	CDD:239037	77/140 (55%)
rnf130	XP_009289393.1	zf-RING_2	271..314	CDD:290367	35/42 (83%)
Rnf130	XP_038942740.1	PA_GRAIL_like	40..179	CDD:239037	77/140 (55%)
		HRD1	<197..366	CDD:227568	132/168 (79%)
		RING-H2_RNF130	262..310	CDD:319717	40/47 (85%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	153	1.000	Domainoid score	I16583
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41267
Inparanoid	1	1.050	490	1.000	Inparanoid score	I6300
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		otm32354
orthoMCL	1	0.900	-	-		OOG6_110755
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	12	11.970