Protein Alignment rnf130 and RNF130

DIOPT Version :10

• Sequence 1: NP_001018301.2
• Gene: rnf130 / 553950
• ZFINID: ZDB-GENE-050522-525
• Length: 428
• Species: Danio rerio
• Sequence 2: NP_060904.2
• Gene: RNF130 / 55819
• HGNCID: 18280
• Length: 419
• Species: Homo sapiens
• Alignment Length: 393
• Identity: 251/393 - (63%)
• Similarity: 302/393 - (76%)
• Gaps: 14/393 - (3%)

Zfish     6 AAPASCSSCLLALLLAFVSPRCSL-SIGADKTMVNKEDYYSAIVNATVLDHKGNPQQMVTKND-G 68
            |.||..::  ||||      .||| ...||..   .::||:|::|.|| ...|....:..:.| |
Human     7 AGPARLAA--LALL------TCSLWPARADNA---SQEYYTALINVTV-QEPGRGAPLTFRIDRG 59

Zfish    69 RYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTRFIVPPKTTHWVAIMQRGKCTFKEKILKAAA 133
            |||.:|||.|.:|.|:||..::|..|..||.|.|||.|||....|:|::|||.|||||||.:||.
Human    60 RYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAF 124

Zfish   134 FNASAVIIYNNNTKEDTVTMAHEGTGDIVAVMITESFGKEILGFLEKNQTVLVSVIVGSRGMPKN 198
            .||.||:||||.:||:.|||.|.|||||:||||||..||:||.:||||.:|.:::.||:|..|||
Human   125 HNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKN 189

Zfish   199 INRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRGD 263
            .:|||||||||||||||||||||||||||||||.|:||||:|||||||||||||||||||||:||
Human   190 FSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGD 254

Zfish   264 KETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNILKALGVMPNLP 328
            |||:|||:|||||||.|:.|||||||||||||||.||||||:|||||||||||||||||::||||
Human   255 KETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLP 319

Zfish   329 CVDNMAFDMDRMSRSQTSSQRTALVDLSSETSISLEPLRHSSSSQLPSDEELIPRSGEINIAVTT 393
            |.||:||||:|::|:|..::|:||.||:.:.|:.|||||.|..|.||.|.||.||:||||||||.
Human   320 CTDNVAFDMERLTRTQAVNRRSALGDLAGDNSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTK 384

Zfish   394 GHF 396
            ..|
Human   385 EWF 387

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf130	NP_001018301.2	PA_GRAIL_like	49..188	CDD:239037	76/139 (55%)
		HRD1	<206..>315	CDD:227568	97/108 (90%)
		RING-H2_RNF130	271..319	CDD:319717	41/47 (87%)
RNF130	NP_060904.2	PA_GRAIL_like	40..179	CDD:239037	76/139 (55%)
		HRD1	<197..>306	CDD:227568	97/108 (90%)
		RING-H2_RNF130	262..310	CDD:319717	41/47 (87%)