Protein Alignment rnf130 and RNF130

DIOPT Version :9

• Sequence 1: XP_009289393.1
• Gene: rnf130 / 553950
• ZFINID: ZDB-GENE-050522-525
• Length: 428
• Species: Danio rerio
• Sequence 2: XP_024301897.1
• Gene: RNF130 / 55819
• HGNCID: 18280
• Length: 448
• Species: Homo sapiens
• Alignment Length: 392
• Identity: 251/392 - (64%)
• Similarity: 303/392 - (77%)
• Gaps: 14/392 - (3%)

Zfish     6 AAPASCSSCLLALLLAFVSPRCSL-SIGADKTMVNKEDYYSAIVNATVLDHKGNPQQMVTKND-G 68
            |.||..::  ||||      .||| ...||..   .::||:|::|.|| ...|....:..:.| |
Human     7 AGPARLAA--LALL------TCSLWPARADNA---SQEYYTALINVTV-QEPGRGAPLTFRIDRG 59

Zfish    69 RYGQNSPKTEAKGIVVAPAAVNGAVDLQGCCPHTRFIVPPKTTHWVAIMQRGKCTFKEKILKAAA 133
            |||.:|||.|.:|.|:||..::|..|..||.|.|||.|||....|:|::|||.|||||||.:||.
Human    60 RYGLDSPKAEVRGQVLAPLPLHGVADHLGCDPQTRFFVPPNIKQWIALLQRGNCTFKEKISRAAF 124

Zfish   134 FNASAVIIYNNNTKEDTVTMAHEGTGDIVAVMITESFGKEILGFLEKNQTVLVSVIVGSRGMPKN 198
            .||.||:||||.:||:.|||.|.|||||:||||||..||:||.:||||.:|.:::.||:|..|||
Human   125 HNAVAVVIYNNKSKEEPVTMTHPGTGDIIAVMITELRGKDILSYLEKNISVQMTIAVGTRMPPKN 189

Zfish   199 INRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISKLTTRTVKRGD 263
            .:|||||||||||||||||||||||||||||||.|:||||:|||||||||||||||||||||:||
Human   190 FSRGSLVFVSISFIVLMIISSAWLIFYFIQKIRYTNARDRNQRRLGDAAKKAISKLTTRTVKKGD 254

Zfish   264 KETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNILKALGVMPNLP 328
            |||:|||:|||||||.|:.|||||||||||||||.||||||:|||||||||||||||||::||||
Human   255 KETDPDFDHCAVCIESYKQNDVVRILPCKHVFHKSCVDPWLSEHCTCPMCKLNILKALGIVPNLP 319

Zfish   329 CVDNMAFDMDRMSRSQTSSQRTALVDLSSETSISLEPLRHSSSSQLPSDEELIPRSGEINIAVTK 393
            |.||:||||:|::|:|..::|:||.||:.:.|:.|||||.|..|.||.|.||.||:||||||||.
Human   320 CTDNVAFDMERLTRTQAVNRRSALGDLAGDNSLGLEPLRTSGISPLPQDGELTPRTGEINIAVTS 384

Zfish   394 EW 395
            :|
Human   385 KW 386

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
rnf130	XP_009289393.1	PA_GRAIL_like	49..188	CDD:239037	76/139 (55%)
		zf-RING_2	271..314	CDD:290367	36/42 (86%)
RNF130	XP_024301897.1	PA_GRAIL_like	40..179	CDD:239037	76/139 (55%)
		zf-rbx1	<197..>306	CDD:331150	97/108 (90%)
		RING_Ubox	262..310	CDD:327409	41/47 (87%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C194333162
Domainoid	1	1.000	153	1.000	Domainoid score	I17425
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41267
Inparanoid	1	1.050	489	1.000	Inparanoid score	I6637
NCBI	1	1.000	-	-
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D1487241at2759
OrthoFinder	1	1.000	-	-		FOG0000832
OrthoInspector	1	1.000	-	-		oto45589
orthoMCL	1	0.900	-	-		OOG6_110755
Panther	1	1.100	-	-	LDO	PTHR22765
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X295
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
ZFIN	1	1.500	-	-
	15	15.400