DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment rnf130 and SPAP32A8.03c

DIOPT Version :9

Sequence 1:	XP_009289393.1	Gene:	rnf130 / 553950	ZFINID:	ZDB-GENE-050522-525	Length:	428	Species:	Danio rerio
Sequence 2:	NP_594179.1	Gene:	SPAP32A8.03c / 2542072	PomBaseID:	SPAP32A8.03c	Length:	513	Species:	Schizosaccharomyces pombe

Alignment Length:	398	Identity:	82/398 - (20%)
Similarity:	144/398 - (36%)	Gaps:	103/398 - (25%)

- Green bases have known domain annotations that are detailed below.

Zfish    42 DYYSAIVNATVLDHKGNPQQMVTKNDGRYGQNSP--KTEAKGIVVAPAAVNGAVDLQGCCPHTRF 104
            :::..|:.......:.|.:|  .:|......|.|  ..:.:|....|::.|.|..:.|...:|..
pombe   150 NFFQNIMGGNAPQPEANSEQ--ARNANTETSNPPFASAQTQGQEHRPSSPNPAEHMTGAYVNTPL 212

Zfish   105 IVPPKTTHWVAIMQRGKCTFKEKILKAAA-------------------------FNASAVI---- 140
            ..||.   :.|..|.........|..:::                         |:|.:.:
pombe   213 NQPPS---YAASTQPEFQQTTSPIFSSSSTPPPPPPRPSQPTSGESQNTNPRFPFSAQSFVFSVG 274

Zfish   141 ----IYNNNTKEDTVTMAHEGTGDIVAVMITE--SFGKEILGFLEK-----------NQTVLVSV 188
                ::..||..:....|..|     |:.||:  |..:.|.|.|.:           |...:.|.
pombe   275 PNGALHQVNTSTENPQNAQAG-----AIPITDLGSILERIFGSLNQPGAQQGEGEPFNPANMFSN 334

Zfish   189 IVGSRGMPKNINRGSLVFVSISFIVLMIISSAWLIFYFIQKIRDTSARDRSQRRLGDAAKKAISK 253
            |....|.|.:...|:.   .:..|:..::..|                 :.......|.:..|:|
pombe   335 IFNLSGNPGDYAWGAR---GLDDIISQLMEQA-----------------QGHNAPAPAPEDVIAK 379

Zfish   254 LTTRTVKRGDKETEPDFNHCAVCIEGYQLNDVVRILPCKHVFHKMCVDPWLNEHCTCPMCKLNIL 318
            :   .|::..||...:...|.:|:|.:::||.|..|||||.||:.|:.|||..:.||.:|:
pombe   380 M---KVQKPPKELIDEEGECTICMEMFKINDDVIQLPCKHYFHENCIKPWLRVNGTCAICR---- 437

Zfish   319 KALGVMPNLPCVDNMAFDM---------DRMSRSQTSSQ----RTALVDLSSETSISLEPLRHSS 370
              ..|.||....:|.:.|.         ...|.|.|:.|    |....:.:|::::|.|   |..
pombe   438 --APVDPNSQQRNNTSTDSANGHNPSNHANPSTSTTNDQGATLRNESFNAASQSNLSSE---HGH 497

Zfish   371 SSQLPSDE 378
            ||:.|.|:
pombe   498 SSRTPMDD 505

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
rnf130	XP_009289393.1	PA_GRAIL_like	49..188	CDD:239037	30/186 (16%)
rnf130	XP_009289393.1	zf-RING_2	271..314	CDD:290367	19/42 (45%)
SPAP32A8.03c	NP_594179.1	HypA	<1..34	CDD:302785
SPAP32A8.03c	NP_594179.1	zf-RING_2	394..437	CDD:290367	19/42 (45%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.910