Protein Alignment TCP11L1 and CG16721

DIOPT Version :10

• Sequence 1: XP_011518506.1
• Gene: TCP11L1 / 55346
• HGNCID: 25655
• Length: 514
• Species: Homo sapiens
• Sequence 2: NP_572275.1
• Gene: CG16721 / 31520
• FlyBaseID: FBgn0029820
• Length: 494
• Species: Drosophila melanogaster
• Alignment Length: 511
• Identity: 163/511 - (31%)
• Similarity: 263/511 - (51%)
• Gaps: 62/511 - (12%)

Human    12 EAGKSKSNDSEEGLEDAVEGADEALQKAIKSDS-SSPQRVQR---P--HSSPPRFVTVEELLETA 70
            ::|:|..::..|             ::.|::|| ||.:.:.|   |  ..:||:.||::|:....
  Fly    10 QSGQSGDHEEHE-------------ERRIRTDSESSVESMTRFVLPSLDGTPPKIVTLDEVSSMF 61

Human    71 RGVTNMALAHEIVVNGDFQIKPVELPENSLKKRVKEIVHKAFWDCLSVQLSEDPPAYDHAIKLVG 135
            :.:.||.|||||.:|.||:::..|.|.:||:..:|::|||||||.|.|||...||:||.||:|:.
  Fly    62 KNLRNMELAHEIALNPDFKLQKYEPPSDSLEGAIKKMVHKAFWDLLRVQLDRQPPSYDQAIRLLA 126

Human   136 EIKETLLSFLLPGHTRLRNQITEVLDLDLIKQEAENGALDISKLAEFIIGMMGTLCAPARDEEVK 200
            ||||.....|.|.:.|....|.||||..:|:|:||.|.||....|.|:|.::...|:|||||.|.
  Fly   127 EIKECFPQLLSPNNERALAHINEVLDDSVIRQQAERGTLDFRAYANFVINILSRSCSPARDEAVA 191

Human   201 KLKDIKEIVPLFREIFSVLDLMKVDMANFAISSIRPHLMQQSVEYERKKFQEILERQPTLFFTDS 265
            .|:.|.::|..||.|..::.|||:|||||.:...|..:...||:||::||.:.|..     |..:
  Fly   192 ALRKIDDVVDTFRCILELMTLMKLDMANFMLRLARTEIAANSVQYEKEKFSKYLRE-----FHGN 251

Human   266 LDFVTQWLEEASEDLMTQKYKHALPVGGMAAGSGDMPRLSPVAVQNYAYLKLLKWDHLQRPFPET 330
            :.|      .|:||.: |:::         :||.|     ...:.| ||::|:.:. ..:.|||.
  Fly   252 VGF------PATEDWL-QRHR---------SGSSD-----DETIYN-AYMQLIDYP-ADKEFPEL 293

Human   331 VLMDQSRFHELQLQLEQLTILGAVLLVTFSMAAPGISSQADFAEKLKMIVKILLTDMHLPSFHLK 395
            :.:|:.||..|..:.::|.:..:  |::.:...|.||.:.:...||...:.|::.|:.    :..
  Fly   294 LRIDKERFAGLSWRAQRLILCAS--LISVAQGMPIISQRRENRIKLAQQLDIIVQDIK----NQD 352

Human   396 DVLTTIGEKVCLE-----VSSCLSLCGSSPFTTDKETVLKGQIQAVASPDDPIRRIMESRILTFL 455
            .|.:||  :.|.|     |:..|........:...:..||.|:..:|:...|:..:|..|:..::
  Fly   353 QVASTI--ESCYEQIRSFVNKALEQENLPALSDADQAALKNQVLKLANKTSPVPSLMAKRLDGYV 415

Human   456 ETYLASGHQKPLPTVPGGLSPVQRELEEVAIKFARLVNYNKMVFCPYYDAILSKIL 511
            ...|.|....|.|  |.|.:..|.||......|.|||:||..||..::..||:|.|
  Fly   416 RVTLRSNGSIPPP--PSGFADYQEELVAFIASFRRLVSYNHAVFGEHFHQILNKTL 469

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
TCP11L1	XP_011518506.1	Tcp11	78..507	CDD:461743	142/433 (33%)
CG16721	NP_572275.1	Tcp11	69..466	CDD:461743	143/434 (33%)