DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment SLC35C1 and Slc35c1

DIOPT Version :9

Sequence 1:	NP_060859.4	Gene:	SLC35C1 / 55343	HGNCID:	20197	Length:	364	Species:	Homo sapiens
Sequence 2:	NP_001101218.1	Gene:	Slc35c1 / 311204	RGDID:	1309463	Length:	363	Species:	Rattus norvegicus

Alignment Length:	364	Identity:	320/364 - (87%)
Similarity:	337/364 - (92%)	Gaps:	1/364 - (0%)

- Green bases have known domain annotations that are detailed below.

Human     1 MNRAPLKRSRILHMALTGASDPSAEAEANGEKPFLLRALQIALVVSLYWVTSISMVFLNKYLLDS 65
            |||.||||||||.|||||||..|.||::. .||||||||||||||||||||||||||||||||||
  Rat     1 MNRVPLKRSRILRMALTGASAVSEEADSE-NKPFLLRALQIALVVSLYWVTSISMVFLNKYLLDS 64

Human    66 PSLRLDTPIFVTFYQCLVTTLLCKGLSALAACCPGAVDFPSLRLDLRVARSVLPLSVVFIGMITF 130
            |||:|||||||||||||||:|||||||.||.||||.||||:|.|||:||||||||||||||||||
  Rat    65 PSLQLDTPIFVTFYQCLVTSLLCKGLSTLATCCPGMVDFPTLNLDLKVARSVLPLSVVFIGMITF 129

Human   131 NNLCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYALLTCGIIIGGFWLGVDQEGAEGTLS 195
            ||||||||||||||||||||||||||||||||||||||||||||.|||||||||:||||||||||
  Rat   130 NNLCLKYVGVAFYNVGRSLTTVFNVLLSYLLLKQTTSFYALLTCAIIIGGFWLGIDQEGAEGTLS 194

Human   196 WLGTVFGVLASLCVSLNAIYTTKVLPAVDGSIWRLTFYNNVNACILFLPLLLLLGELQALRDFAQ 260
            ..||:||||||||||||||||.|||||||.||||||||||||||:|||||:::||||.||..||.
  Rat   195 LTGTIFGVLASLCVSLNAIYTKKVLPAVDHSIWRLTFYNNVNACVLFLPLMVVLGELHALLAFAH 259

Human   261 LGSAHFWGMMTLGGLFGFAIGYVTGLQIKFTSPLTHNVSGTAKACAQTVLAVLYYEETKSFLWWT 325
            |.|||||.|||||||||||||||||||||||||||||||||||||||||||||||||.|||||||
  Rat   260 LNSAHFWVMMTLGGLFGFAIGYVTGLQIKFTSPLTHNVSGTAKACAQTVLAVLYYEEIKSFLWWT 324

Human   326 SNMMVLGGSSAYTWVRGWEMKKTPEEPSPKDSEKSAMGV 364
            ||:|||||||||||||||||:||.|:||.|:.||||:||
  Rat   325 SNLMVLGGSSAYTWVRGWEMQKTQEDPSSKEGEKSAIGV 363

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
SLC35C1	NP_060859.4	EamA	42..183	CDD:304911	131/140 (94%)
Slc35c1	NP_001101218.1	TPT	38..302	CDD:281186	238/263 (90%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C83686179
Domainoid	1	1.000	508	1.000	Domainoid score	I7008
eggNOG	1	0.900	-	-		E1_KOG1442
HGNC	1	1.500	-	-
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H41258
Inparanoid	1	1.050	639	1.000	Inparanoid score	I9634
NCBI	1	1.000	-	-
OMA	1	1.010	-	-		QHG54539
OrthoDB	1	1.010	-	-		D114679at9347
OrthoFinder	1	1.000	-	-		FOG0005416
OrthoInspector	1	1.000	-	-		oto129551
orthoMCL	1	0.900	-	-		OOG6_104078
Panther	1	1.100	-	-	LDO	PTHR11132
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X1680
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	17	17.310