Protein Alignment ACER3 and bwa

DIOPT Version :10

• Sequence 1: NP_060837.3
• Gene: ACER3 / 55331
• HGNCID: 16066
• Length: 267
• Species: Homo sapiens
• Sequence 2: NP_001260616.1
• Gene: bwa / 250736
• FlyBaseID: FBgn0045064
• Length: 300
• Species: Drosophila melanogaster
• Alignment Length: 278
• Identity: 85/278 - (30%)
• Similarity: 126/278 - (45%)
• Gaps: 67/278 - (24%)

Human    13 PTTSTLDWCEENYSVTWYIAEFWNTVSN-LIMIIPPM-------FGAVQSVRDGLEKRYIASYLA 69
            |.:|.:||||.||.::..||||.||.|| |.:::||:       :|  :.|..|:.    ..::.
  Fly    22 PGSSPVDWCEGNYLISSNIAEFVNTFSNFLFILLPPVLIMLFKEYG--RFVTPGIH----VIWVL 80

Human    70 LTVVGMGSWCFHMTLKYEMQLLDELPMIYSCCIFVYCMFECFKIKNSVNYHLLFT---------L 125
            |.|||:.|..||.||....||||||.:::   :|: ..|..|..|   .|:..|.         |
  Fly    81 LIVVGLSSMYFHATLSLIGQLLDELAILW---VFM-AAFSLFYPK---RYYPKFVKNDRKTFSWL 138

Human   126 VLFSLIVTTVYLKVKEPIFHQVMYGMLVFTLVLRSIYIVTWVYPWLR--------GLGYTSLGIF 182
            :|.|.|..| .|...:||.:       .|.|:..|:..:..:|..|:        .||..|..::
  Fly   139 MLLSAIAAT-GLSWWKPIVN-------AFVLMFMSVPTMVMLYTELQRVSDQRVYRLGIRSTTVW 195

Human   183 LLGFLFWNIDNIFCE--SLRNFRKKVPPIIGITTQFHAWWHILTGLGSY-LHILFSLY------- 237
            .:....|..|.||||  |..||     |.:      |.:|||...:.:| :.:||:.:
  Fly   196 AVAVFCWINDRIFCEAWSSINF-----PYL------HGFWHIFIFIAAYTVLVLFAYFYVESELP 249

Human   238 TRTLYLRYRPKVKFLFGI 255
            .|...|:|.||.:|.|||
  Fly   250 QRQPLLKYWPKNEFEFGI 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
ACER3	NP_060837.3	Ceramidase	12..263	CDD:461766	85/278 (31%)
bwa	NP_001260616.1	Ceramidase	22..271	CDD:461766	85/278 (31%)