Protein Alignment PPP3CB and Pp1-Y1

DIOPT Version :10

• Sequence 1: XP_047281382.1
• Gene: PPP3CB / 5532
• HGNCID: 9315
• Length: 534
• Species: Homo sapiens
• Sequence 2: NP_001104152.3
• Gene: Pp1-Y1 / 5740113
• FlyBaseID: FBgn0261399
• Length: 317
• Species: Drosophila melanogaster
• Alignment Length: 284
• Identity: 111/284 - (39%)
• Similarity: 160/284 - (56%)
• Gaps: 31/284 - (10%)

Human    49 IPRVDVLKNHLVKEGRVDEEIALRIINEGAAILRREKTMIEVEAPITVCGDIHGQFFDLMKLFEV 113
            :|..|::|  |:|:.|              .:|..|..::.||||:.|.||||||:.||::.||.
  Fly    35 VPESDIIK--LLKQAR--------------QVLMSEPMLLTVEAPVNVLGDIHGQYNDLLRYFET 83

Human   114 GGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLRGNHECRHLTEYFTFKQECKIK 178
            .|.|...|||.||||||||.:|:|.:..|...|:.||:::.|||||||...:..|:.|..|||.:
  Fly    84 SGHPPKKRYLMLGDYVDRGKYSVETLTLLLAYKVRYPTSIHLLRGNHESAAINRYYGFYDECKRR 148

Human   179 YSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIRRLDRFKEPPAFGPMCDLLWSD 243
            ::.|::...::.:|.||:||::|.:..|.||||||.:|.|:||:.|.|..|....|.:|||||||
  Fly   149 FTIRLWRMFVDCYDCLPVAAIINSKIFCCHGGLSPSLHNLNDIQHLQRPAEVDRNGLLCDLLWSD 213

Human   244 PSED-FGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSIIRAHEAQDAGYRMYRKSQTTG 307
            |... .|.||:.        ||.|:.:....|..||...:...|.|||:..:.||..:.|.|
  Fly   214 PDPTAIGWEKNS--------RGVSFTFGVDIVETFLSRFSFDLICRAHQVVEDGYEFFAKRQ--- 267

Human   308 FPSLITIFSAPNYLDVYNNKAAVL 331
               |||:|||.||...::|..|::
  Fly   268 ---LITVFSAVNYCGEFDNAGAMM 288

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP3CB	XP_047281382.1	MPP_PP2B	50..354	CDD:277361	111/283 (39%)
Pp1-Y1	NP_001104152.3	MPP_superfamily	17..303	CDD:472684	111/284 (39%)