Protein Alignment PPP3CB and PpD5

DIOPT Version :10

• Sequence 1: XP_047281382.1
• Gene: PPP3CB / 5532
• HGNCID: 9315
• Length: 534
• Species: Homo sapiens
• Sequence 2: NP_524707.1
• Gene: PpD5 / 44148
• FlyBaseID: FBgn0005778
• Length: 346
• Species: Drosophila melanogaster
• Alignment Length: 331
• Identity: 122/331 - (36%)
• Similarity: 186/331 - (56%)
• Gaps: 33/331 - (9%)

Human    35 THRLTSEEVFDLDGIPRVDVLKNHLV-------KEGRVDEEIALRIINEGAAILRREKTMIEVEA 92
            |.:.:|:|  :.:.:.::||:...|.       :.|.:.|.....|......:...:..::|:.|
  Fly    10 TGKESSKE--EKNRMSQLDVIIGQLKTMAVGNRRAGNLSEATITYICQASRELFLSQPMLLELSA 72

Human    93 PITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPSTLFLLR 157
            |:.:|||:||||.||:::|:..|.|..:.|||||||||||:.|||.:..|...|:.||.|.||||
  Fly    73 PVKICGDLHGQFKDLLRIFQQCGVPPLSNYLFLGDYVDRGHCSIETLSLLLTYKLRYPETFFLLR 137

Human   158 GNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIHTLDDIR 222
            ||||...|...:.|..|||.:||.:::.:.::.:|.:|:||::..:..||||||||:::.|||||
  Fly   138 GNHESADLNRVYGFFDECKRRYSIKLWRSFVDCYDCMPVAAIIADRIFCVHGGLSPDLNNLDDIR 202

Human   223 RLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNNNLLSII 287
            ||:|..:.|:.|.:||||||||.|..|...|.:       ||.|:.:....|..||..:....|:
  Fly   203 RLNRPTDVPSDGLLCDLLWSDPDETTGTWASND-------RGVSFTFGANIVEGFLMQHKFNLIV 260

Human   288 RAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNC-----SP 347
            |||:..:.||..:...|      |:||||||||.|:::|..|||..:..::      |     .|
  Fly   261 RAHQVVEDGYEFFADRQ------LVTIFSAPNYCDIFDNCGAVLVVDAKLV------CHFVIIRP 313

Human   348 HPYWLP 353
            .|:..|
  Fly   314 RPFSRP 319

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP3CB	XP_047281382.1	MPP_PP2B	50..354	CDD:277361	119/316 (38%)
PpD5	NP_524707.1	MPP_superfamily	25..313	CDD:472684	116/306 (38%)