Protein Alignment PPP3CB and ppb1

DIOPT Version :10

• Sequence 1: XP_047281382.1
• Gene: PPP3CB / 5532
• HGNCID: 9315
• Length: 534
• Species: Homo sapiens
• Sequence 2: NP_596178.1
• Gene: ppb1 / 2540024
• PomBaseID: SPBP4H10.04
• Length: 554
• Species: Schizosaccharomyces pombe
• Alignment Length: 533
• Identity: 317/533 - (59%)
• Similarity: 398/533 - (74%)
• Gaps: 51/533 - (9%)

Human    24 DRVVKAVPFPPTHRLTSEEVFDLDGIPRVDV--LKNHLVKEGRVDEEIALRIINEGAAILRREKT 86
            |||||.|..|.|:..|..|.||::...:.|:  |:||.::|||:.||..|.||.:...||:.|..
pombe    42 DRVVKNVQAPATYIPTDVEFFDINEPDKPDLHFLRNHFIREGRLSEEQTLYIIKKATEILKSEDN 106

Human    87 MIEVEAPITVCGDIHGQFFDLMKLFEVGGSPANTRYLFLGDYVDRGYFSIECVLYLWVLKILYPS 151
            :|||:||:|||||||||::||||||||||:||||:|||||||||||||||||:||||.|||.||.
pombe   107 LIEVDAPVTVCGDIHGQYYDLMKLFEVGGNPANTQYLFLGDYVDRGYFSIECLLYLWALKIWYPK 171

Human   152 TLFLLRGNHECRHLTEYFTFKQECKIKYSERVYEACMEAFDSLPLAALLNQQFLCVHGGLSPEIH 216
            ||:||||||||.|||:|||||.||..||:.:|||||:::|::|||||::|:||||||||||||:|
pombe   172 TLWLLRGNHECAHLTDYFTFKLECTHKYNIKVYEACLQSFNALPLAAIMNKQFLCVHGGLSPELH 236

Human   217 TLDDIRRLDRFKEPPAFGPMCDLLWSDPSEDFGNEKSQEHFSHNTVRGCSYFYNYPAVCEFLQNN 281
            ||:|||.::||.|||..|.|||||||||.||||:|||.:||.||.||||||||:|.|||.||:||
pombe   237 TLNDIRMINRFCEPPTHGLMCDLLWSDPLEDFGSEKSNKHFIHNNVRGCSYFYSYQAVCTFLENN 301

Human   282 NLLSIIRAHEAQDAGYRMYRKSQTTGFPSLITIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 346
            ||||:||||||||.|||||||::|||||||:||||||||||||||||||||||||||||||||||
pombe   302 NLLSVIRAHEAQDVGYRMYRKTKTTGFPSLMTIFSAPNYLDVYNNKAAVLKYENNVMNIRQFNCS 366

Human   347 PHPYWLPNFMDVFTWSLPFVGEKVTEMLVNVLSICSDDELM-----------------TEGEDQF 394
            ||||||||||||||||||||||||:|||:::|:|||.:||.                 :|.|::.
pombe   367 PHPYWLPNFMDVFTWSLPFVGEKVSEMLISMLNICSKEELYETDLKESAPTQHKQPAPSENENKA 431

Human   395 DERLIYGNKKVGSAAARKEIIRNKIRAIGKMARVFSVLREESESVLTLKGLTPTGMLPSGVLAGG 459
            |:.:        ...||::||:|||.|||:::|||||||||.|||..||.::.|..||:|.|..|
pombe   432 DQEI--------DIEARRQIIKNKIMAIGRISRVFSVLREERESVSELKNVSGTQRLPAGTLMLG 488

Human   460 RQTLQSATVEAIEAEKAIRGFSPPHRICSFEEAKGLDRINERMPP---RKDAVQQDGFNSLNTAH 521
            .:.:::|                   |.||::|:.||..|||:||   |:.:.....|..:  .:
pombe   489 AEGIKNA-------------------INSFDDARKLDIQNERLPPSNSRRRSTDLKAFEEV--MN 532

Human   522 ATENHGTGNHTAQ 534
            ::|:..:.:|..:
pombe   533 SSEDDTSIDHLVE 545

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PPP3CB	XP_047281382.1	MPP_PP2B	50..354	CDD:277361	229/305 (75%)
ppb1	NP_596178.1	MPP_PP2B	70..374	CDD:277361	229/303 (76%)