Protein Alignment RHOT1 and Rhot1

DIOPT Version :10

• Sequence 1: XP_047292309.1
• Gene: RHOT1 / 55288
• HGNCID: 21168
• Length: 722
• Species: Homo sapiens
• Sequence 2: NP_001391057.1
• Gene: Rhot1 / 59040
• MGIID: 1926078
• Length: 752
• Species: Mus musculus
• Alignment Length: 747
• Identity: 665/747 - (89%)
• Similarity: 680/747 - (91%)
• Gaps: 53/747 - (7%)

Human    29 VSPVARTDLAQKRH-----SARVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVD 88
            |.|:..:|:.:...     ..||||||||||||||||||||||||||||||||||||||||||||
Mouse     6 VRPLRASDMKKDVRILLVGEPRVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVD 70

Human    89 YSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 153
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse    71 YSEAEQSDEQLHQEISQANVICIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDL 135

Human   154 VEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIK 218
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   136 VEYSSMETILPIMNQYTEIETCVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIK 200

Human   219 ALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFL 283
            |||||||||||||||||||||||||||||||||||||||||||||||||:|||||||||||:|||
Mouse   201 ALTRIFKISDQDNDGTLNDAELNFFQRICFNTPLAPQALEDVKNVVRKHLSDGVADSGLTLRGFL 265

Human   284 FLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHD 348
            |||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   266 FLHTLFIQRGRHETTWTVLRRFGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHD 330

Human   349 LDRDCALSPDELKDLFKVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLG 413
            ||||||||||||||||:||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   331 LDRDCALSPDELKDLFQVFPYIPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLG 395

Human   414 YLGYSILTEQESQASAVTVTRDKKIDLQKKQTQRNVFRCNVIGVKNCGKSGVLQALLGRNLMRQK 478
            ||||||||||||||||:||||||||||||||||||||||||||||.|||:||||:||||||||||
Mouse   396 YLGYSILTEQESQASAITVTRDKKIDLQKKQTQRNVFRCNVIGVKGCGKTGVLQSLLGRNLMRQK 460

Human   479 KIREDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAEIICDVVCLVYDVSNPKSFEYCARIFK 543
            |||:|||||||||||||||||||||||||||||||||||.|||||||||||:|||||||||||||
Mouse   461 KIRDDHKSYYAINTVYVYGQEKYLLLHDISESEFLTEAETICDVVCLVYDVTNPKSFEYCARIFK 525

Human   544 QHFMDSRIPCLIVAAKSDLHEVKQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMA 608
            |||||||||||||||||||||||||:|||||||||||||||||||||||||||||||||||||||
Mouse   526 QHFMDSRIPCLIVAAKSDLHEVKQEHSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMA 590

Human   609 MYPEDHYRDRLSRDMGHTDRIENLRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSV 673
            ||||||||..||||||.||||||||||||||||||||||||||||||||||||||||||||||||
Mouse   591 MYPEDHYRGSLSRDMGSTDRIENLRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSV 655

Human   674 KNKIFTAVLN------------------------------------------------RHVTQAD 690
            ||||||||||                                                |||||||
Mouse   656 KNKIFTAVLNRLKARVAEWGAMLLADDEGSITHQVHAVSSVEDSIFMESSHGQLFLDDRHVTQAD 720

Human   691 LKSSTFWLRASFGATVFAVLGFAMYKALLKQR 722
            |||||||||||||||||||:|||||:||||||
Mouse   721 LKSSTFWLRASFGATVFAVVGFAMYRALLKQR 752

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOT1	XP_047292309.1	Miro1	46..200	CDD:206680	153/153 (100%)
		EF_assoc_2	250..334	CDD:462444	81/83 (98%)
		EF_assoc_1	372..441	CDD:462443	67/68 (99%)
		Miro2	446..611	CDD:206679	157/164 (96%)
Rhot1	NP_001391057.1	Miro1	16..182	CDD:206680	154/165 (93%)
		EF_assoc_2	232..316	CDD:462444	81/83 (98%)
		EF_assoc_1	354..423	CDD:462443	67/68 (99%)
		Miro2	428..593	CDD:206679	157/164 (96%)