Protein Alignment RHOT1 and rhot1

DIOPT Version :10

• Sequence 1: XP_047292309.1
• Gene: RHOT1 / 55288
• HGNCID: 21168
• Length: 722
• Species: Homo sapiens
• Sequence 2: XP_031750214.1
• Gene: rhot1 / 100492251
• XenbaseID: XB-GENE-494893
• Length: 707
• Species: Xenopus tropicalis
• Alignment Length: 666
• Identity: 525/666 - (78%)
• Similarity: 580/666 - (87%)
• Gaps: 45/666 - (6%)

Human    45 RVGKTSLIMSLVSEEFPEEVPPRAEEITIPADVTPERVPTHIVDYSEAEQSDEQLHQEISQANVI 109
            ||||||||||||.||||||||.||||||||.|||||||||||||||||||:|:||:.|||:||||
 Frog    14 RVGKTSLIMSLVGEEFPEEVPARAEEITIPGDVTPERVPTHIVDYSEAEQTDDQLYMEISRANVI 78

Human   110 CIVYAVNNKHSIDKVTSRWIPLINERTDKDSRLPLILVGNKSDLVEYSSMETILPIMNQYTEIET 174
            ||||||||::||||||:.||||||||||||:|:|||||||||||::|||:||||||||||:||||
 Frog    79 CIVYAVNNRNSIDKVTNHWIPLINERTDKDNRVPLILVGNKSDLLDYSSLETILPIMNQYSEIET 143

Human   175 CVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKEMKPACIKALTRIFKISDQDNDGTLNDAE 239
            |||||||||||||||||||||||||||||||||||||:||||:|||||||||||.|||..|||||
 Frog   144 CVECSAKNLKNISELFYYAQKAVLHPTGPLYCPEEKELKPACVKALTRIFKISDMDNDRILNDAE 208

Human   240 LNFFQRICFNTPLAPQALEDVKNVVRKHISDGVADSGLTLKGFLFLHTLFIQRGRHETTWTVLRR 304
            |||||||||:.||||||||||||||||::.|||:.:|||||||||||||||||||||||||||||
 Frog   209 LNFFQRICFHIPLAPQALEDVKNVVRKNVLDGVSANGLTLKGFLFLHTLFIQRGRHETTWTVLRR 273

Human   305 FGYDDDLDLTPEYLFPLLKIPPDCTTELNHHAYLFLQSTFDKHDLDRDCALSPDELKDLFKVFPY 369
            |||||||:||||||||.||:|.||||||||||||||||.|||||.||||||||:||||||:||||
 Frog   274 FGYDDDLELTPEYLFPQLKVPIDCTTELNHHAYLFLQSIFDKHDQDRDCALSPEELKDLFQVFPY 338

Human   370 IPWGPDVNNTVCTNERGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQASAVTVTR 434
            :||||||||||.|||:||||||||||||||||||||||||||||||||||||||||||.||||||
 Frog   339 MPWGPDVNNTVYTNEKGWITYQGFLSQWTLTTYLDVQRCLEYLGYLGYSILTEQESQAMAVTVTR 403

Human   435 DKKIDLQKKQTQRNVFRCNVIGVKNCGKSGVLQALLGRNLMRQKKIREDHKSYYAINTVYVYGQE 499
            ||||||.|:|||||||||||||.:..||||:||:.|||||||||::||:|||:||||.|||||||
 Frog   404 DKKIDLHKRQTQRNVFRCNVIGSQGSGKSGILQSHLGRNLMRQKRVREEHKSFYAINPVYVYGQE 468

Human   500 KYLLLHDISESEFLTEAEIICDVVCLVYDVSNPKSFEYCARIFKQHFMDSRIPCLIVAAKSDLHE 564
            ||||||.|.|||.|:.|:.:||||||:|||:||.||:||||||||||||||.|||:|||||||||
 Frog   469 KYLLLHHIVESEALSPADTLCDVVCLLYDVANPHSFDYCARIFKQHFMDSRTPCLLVAAKSDLHE 533

Human   565 VKQEYSISPTDFCRKHKMPPPQAFTCNTADAPSKDIFVKLTTMAMYPEDHYRDRLSRDMGHTDRI 629
            ||||.||||.:||:|||||||||||||||::||::||:|:|||||||
 Frog   534 VKQESSISPAEFCKKHKMPPPQAFTCNTAESPSREIFIKMTTMAMYP------------------ 580

Human   630 ENLRKIWVFLKTAFHARLRCMCTCNRCTFCICQNFLNSDLLQSVKNKIFTAVLNRHVTQADLKSS 694
                          ||||||:|||||||||:|||.|||.||||||||:||..:||
 Frog   581 --------------HARLRCLCTCNRCTFCLCQNLLNSHLLQSVKNKLFTGAINR---------- 621

Human   695 TFWLRASFGATVFAVL 710
               |||:..|...|:|
 Frog   622 ---LRAAIDALGDALL 634

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
RHOT1	XP_047292309.1	Miro1	46..200	CDD:206680	135/153 (88%)
		EF_assoc_2	250..334	CDD:462444	72/83 (87%)
		EF_assoc_1	372..441	CDD:462443	65/68 (96%)
		Miro2	446..611	CDD:206679	128/164 (78%)
rhot1	XP_031750214.1	Miro1	3..169	CDD:206680	136/154 (88%)
		EF_assoc_2	220..303	CDD:462444	72/82 (88%)
		EF_assoc_1	341..409	CDD:462443	64/67 (96%)
		Miro2	415..581	CDD:206679	130/197 (66%)