Protein Alignment FGGY and CG1271

DIOPT Version :10

• Sequence 1: NP_001106882.1
• Gene: FGGY / 55277
• HGNCID: 25610
• Length: 575
• Species: Homo sapiens
• Sequence 2: NP_647763.1
• Gene: CG1271 / 38364
• FlyBaseID: FBgn0035392
• Length: 556
• Species: Drosophila melanogaster
• Alignment Length: 632
• Identity: 135/632 - (21%)
• Similarity: 218/632 - (34%)
• Gaps: 160/632 - (25%)

Human     2 SGGEQKPERYYVGVDVGTGSVRAALVDQSGVLLAFADQPIKNWEPQFNHHEQSSEDIWAACCVVT 66
            ||....| .:.:.:||||..||:.::|:...:...|...::...||..:.|...|.:|.....|.
  Fly    24 SGPPDSP-AFILALDVGTTCVRSFVLDEQCEVRGSAVDAVELLNPQPGYFEIEPESLWRKIVGVI 87

Human    67 KKVVQGIDLNQIRGLGFDATCSLVVLDKQFHPLPVNQEGDSHRNVIMWLDHRAVSQVNRINE--T 129
            .:.|:...|...     |.||..:...:.......::.|:.:.|.|.|.|.||...|::.|.  |
  Fly    88 TQAVKNAQLTPP-----DITCLTISTQRCTFLTWDHRSGEYYHNFITWKDLRADELVDQWNASWT 147

Human   130 KH---------------------SVLQYVGGVMSVEMQAPKLLW---LKENLREICWDKAGHFFD 170
            |.                     ||||.:.|.::     |:||:   ..:.|::....|... .:
  Fly   148 KSSMNWFSYALFLLTRQSRFLAGSVLQLMNGQVT-----PRLLFEIMNNKKLKQALMQKKAR-VE 206

Human   171 LPDFLSW----------------KATGVTARSLCSLVCKWTYSAEKGWDDSFWKMIGLEDFVADN 219
            |.|  ||                ..|.||:.:...|...:|.|    |......:.|:.
  Fly   207 LLD--SWILHKLRTGSSRDKDVEHITDVTSSTATGLYDPFTLS----WSPLISWLFGIN------ 259

Human   220 YSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVAASLIDAHAGGLGVIGADVRGHGLICEGQP 284
             |||..:|:..|......:.|.|.........|.:||||.|
  Fly   260 -SKILPRVVDNGYKGFGHVHPTAFGPDWANTEIPIAASLSD------------------------ 299

Human   285 VTSRLAVICGTSSCHMGISKDPIFVPGVWGPYFSAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFP 349
               :.|.|.| |.|   ..|:.:.|         .|..|.:||    .|||.....::.|.....
  Fly   300 ---QTAAIWG-SQC---FQKNDVKV---------TMGTGAFLN----LVTGDRCQAVISGMYPLV 344

Human   350 ELQVKATARCQ-SIYAYLNSHLDLIKKAQPVGFLTVDLHVWP------DFHGNRSPLADLTLKGM 407
            ..|.|...|.| ::|....:..|         |.||  ..|.      |...|.|   |:.....
  Fly   345 AWQFKKPTRQQGAVYCIEGASHD---------FGTV--VTWAQSCELFDSPANTS---DIAQSVP 395

Human   408 RTTGYLYIPALAALHSPSS---------LLSPQVTGLKLSQDLDDLAILYLATVQAIALGTRFII 463
            .|....::||.:.|..|.:         .|:|..|          .|.:..|.:::|......:|
  Fly   396 DTNDVFFMPAFSGLGPPVNDYRSASGFIGLTPSTT----------KAHMVRALLESIVFRLVQLI 450

Human   464 EAME-AAGHSISTLFLCGGLSKNPLFVQMHADITGMPVVLSQEVESVLVGAAVLGACASGDFASV 527
            ||.| .....:..:.:.||:|:|....|..||::.:.|..:...||.::||..:.....|.:..|
  Fly   451 EAAEKETSQKLHMIRVDGGVSRNDFVCQFLADLSRLRVERADNAESSIMGATFMAGINLGIWRDV 515

Human   528 QEAMAKMSKVGKVVFPRLQDKKYYDKKYQVFLKLVEHQKEYLAIMND 574
            .: :.:..||.:|..||       .|:|:.....::.....:|..:|
  Fly   516 ND-LKRFRKVARVFEPR-------PKEYETIANRMDKWSRTIARFSD 554

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGGY	NP_001106882.1	ASKHA_NBD_FGGY_D-RBK	11..568	CDD:466800	130/615 (21%)
CG1271	NP_647763.1	ASKHA_NBD_FGGY_GK5-like	32..549	CDD:466803	130/616 (21%)