Protein Alignment FGGY and CG8298

DIOPT Version :10

• Sequence 1: NP_001106882.1
• Gene: FGGY / 55277
• HGNCID: 25610
• Length: 575
• Species: Homo sapiens
• Sequence 2: NP_610718.1
• Gene: CG8298 / 36282
• FlyBaseID: FBgn0033673
• Length: 596
• Species: Drosophila melanogaster
• Alignment Length: 566
• Identity: 112/566 - (19%)
• Similarity: 182/566 - (32%)
• Gaps: 187/566 - (33%)

Human    33 LLAFADQPIKNWEPQFNHHEQSSEDIWAAC--CVVT---KKVVQGIDLNQIRGLGFDATCSLVVL 92
            :||:.:..::....|....|....:||...  |:.|   ..|:..|:...|..:|.
  Fly    35 VLAYHELKLRQIVHQAGWMEYDPSEIWKNTQECIETAYKNLVILEINPRDIIAIGI--------- 90

Human    93 DKQFHPLPVNQEGDS-----------HRNVIMWLDHRAVSQVNR-INETKHSV--LQYVGGV-MS 142
                    |||.|.|           | |.|.|.|.|:...:.. ::..:|:|  ::|..|: :|
  Fly    91 --------VNQRGTSVLWNLETGQPLH-NAIGWSDCRSTPILKTLLHNVRHNVDYVRYRSGLPLS 146

Human   143 VEMQAPKLLWLKENLREICW---DKAGHFFDLPDFLSWKATG----------VTARSLCSLVCKW 194
            ....|.|:.||.:::..:..   :....|..|..:|.|..||          :|.....||:
  Fly   147 SCFSALKIRWLMDHVPAVATAIEENKCLFGTLDSWLLWNLTGGVEMGVHSTDITNAHYTSLM--- 208

Human   195 TYSAEKGWDD---SFWKM-IGLEDFVADNYSKIGNQVLPPGASLGNGLTPEAARDLGLLPGIAVA 255
            ..|.|: ||.   .|::: :.:...:..| |:|...||.                 |.|.|..:|
  Fly   209 NVSTEQ-WDPKLCQFFRLPLNILPRIRSN-SEIFGYVLE-----------------GPLHGTPIA 254

Human   256 ASLIDAHAGGLGVIGADVRGHGLICEGQPVTSRLAVICGTSSCHMGISKDPIFV----------- 309
            |.:.:..|..||                    :|.|..|.:.|.:   .|..||
  Fly   255 AMMGEQPASLLG--------------------QLCVKAGQNVCTL---DDSCFVLLNTGREKLDS 296

Human   310 -----PGVWGPYFSAMVPGFWLNEGGQSVTGKLI----------------DHMVQGHAAFPELQV 353
                 .|:...........:.| ||..|..|..:                |::|:....|.....
  Fly   297 ANGLITGIAHKLGEKAATNYTL-EGAISNAGSTVTWLRDKLQINTEINSNDNVVESLNTFIGENS 360

Human   354 KATARCQSIYAYLNSHLDLIKKAQPVGFLTVDLHVWPDFHGNRSPLADLTLKGMRTTGYLYIPAL 418
            ..::.|.|  :.||:...|..|...:.|:       |.|||..:|......:|:
  Fly   361 MISSSCSS--SMLNAECGLAAKRSEITFV-------PAFHGMYAPYWRHDARGI----------- 405

Human   419 AALHSPSSLLSPQVTGLKLSQDLDDLAILYLATVQAIALGTRF-IIEAMEAAGH--------SIS 474
                         :.||......:::       .||....|.| |.|.::|...        |:.
  Fly   406 -------------ILGLTSQTTAENI-------TQAAYEATGFQIFEVLQAFKRDTPNWDRSSMQ 450

Human   475 TLFLCGG-LSKNPLFVQMHADITG----MPVVLSQEVESVLVGAAV 515
            .:...|| .::|...||..|||.|    .|...|.....|::.|.|
  Fly   451 PVLTFGGDYAENLHLVQFIADIIGYMLERPQTTSPAGLGVMITAGV 496

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGGY	NP_001106882.1	ASKHA_NBD_FGGY_D-RBK	11..568	CDD:466800	112/566 (20%)
CG8298	NP_610718.1	ASKHA_ATPase-like	19..540	CDD:483947	112/566 (20%)