Protein Alignment FGGY and CG10793

DIOPT Version :10

• Sequence 1: NP_001106882.1
• Gene: FGGY / 55277
• HGNCID: 25610
• Length: 575
• Species: Homo sapiens
• Sequence 2: NP_570054.2
• Gene: CG10793 / 31308
• FlyBaseID: FBgn0288967
• Length: 479
• Species: Drosophila melanogaster
• Alignment Length: 497
• Identity: 91/497 - (18%)
• Similarity: 157/497 - (31%)
• Gaps: 177/497 - (35%)

Human   181 GVTARSLCSLVCK----------------WTYSAEKGWDDSFWKMIGLEDFVADNY--------- 220
            ||||.:...::|:                ..|..|.|:..|. :.:..|..:.|.|
  Fly     8 GVTATAAAQILCEDVRNFSTRRRNILYLMHRYLVENGYYASA-ESLKSEGRLTDEYELCDNIDLD 71

Human   221 ---------------------SKIGNQVLPPGASLGNGLTPE--AARDLGLLPGIAVAASLIDAH 262
                                 .|:|.::   ...:|.|...|  .|::|...|. ...|||.:.|
  Fly    72 AMYLEYASFYNMKFGKYPKILKKVGAKI---KVEMGGGKAHEKTPAKELPKKPP-TTDASLANWH 132

Human   263 AGGLGVIGADVRGHGLICEGQPVTSRLAV----------ICGTSSCHMGISKDPIFVPGVWGPYF 317
            .|    :||..:.   :...||:..:...          .|.....|:| ..|.:|....|
  Fly   133 IG----VGAATQA---LSNEQPLQIKKMETATESNGQDNACEIEHVHLG-GDDVLFSSLEW---- 185

Human   318 SAMVPGFWLNEGGQSVTGKLIDHMVQGHAAFPELQVKATARCQSIYAYLNSHLDLIKKA--QPVG 380
                         ||:.     .:|:.......:::|.:..|.:..|     ::|||:|  .|:.
  Fly   186 -------------QSLA-----ELVKTSILQENIKIKWSDVCGNQRA-----IELIKEAVLTPIE 227

Human   381 FLTVDLH---VWPD--FHGNRSPLADLTLKGM--RTTG---YLYIPA------------------ 417
            |..:..|   .|..  .||.......|..|.:  .|.|   :..|.|
  Fly   228 FPQLFAHGLKPWRSLLLHGPPGSGKTLLAKALYSETQGQVTFFNITASIMVSKWRGESEKILRVL 292

Human   418 --LAALHSPSSLLSPQVTGL------------------KLSQDLDDL-----AILYLATVQA--- 454
              :||..:||.:...::..|                  :|.|.||.:     .:..||:...
  Fly   293 FHMAAKRAPSVIFFDEIESLTSKRDRATDHESSKRFKNELLQLLDGMEHSLNGVFVLASTNLPWD 357

Human   455 --IALGTRF----IIEAMEAAGHS-ISTLFLCGGLSKNPLFVQMHADI----TGMPVVLS-QEVE 507
              .|...||    :::...||..| :....|...:|.||..::...:|    ||..:.|: :|:.
  Fly   358 IDEAFLRRFEKKLLVQLPNAAERSCLINRLLGSSISLNPRLLEQLVEISDHFTGDEIRLACKEIS 422

Human   508 ------SVLVGAAVLGACASGDFASVQEAMAKMSKVGKVVFP 543
                  :..:|...:|..|....|:::   |.:.|..:.|.|
  Fly   423 MHRVRCATKIGDRSIGLLAKESPAAIE---ANVEKAFRQVRP 461

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
FGGY	NP_001106882.1	ASKHA_NBD_FGGY_D-RBK	11..568	CDD:466800	91/497 (18%)
CG10793	NP_570054.2	LisH	31..55	CDD:462501	4/24 (17%)
		RecA-like_VPS4-like	208..372	CDD:410917	32/168 (19%)