Protein Alignment PHF10 and phf10

DIOPT Version :10

• Sequence 1: XP_054211755.1
• Gene: PHF10 / 55274
• HGNCID: 18250
• Length: 512
• Species: Homo sapiens
• Sequence 2: XP_012818532.1
• Gene: phf10 / 595031
• XenbaseID: XB-GENE-940958
• Length: 541
• Species: Xenopus tropicalis
• Alignment Length: 526
• Identity: 376/526 - (71%)
• Similarity: 404/526 - (76%)
• Gaps: 86/526 - (16%)

Human    67 MAAAAGPGAALSPRPCDSDPATPGAQSPKDDN-------EDNSNDGTQPSKRRRMGSGDSSRSCE 124
            |||...|...|    |||:||||...|.|:||       |:|||||:||:||||. ||||:.|||
 Frog    22 MAAVVSPAKPL----CDSEPATPAPPSVKEDNSNDTKDTEENSNDGSQPAKRRRT-SGDSTPSCE 81

Human   125 TSSQDLGFSYYPAENLIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYL 189
            .|:||.|.||:||||:|||||||||||||||||||||||||||||||||||||||||||||||||
 Frog    82 NSNQDFGSSYFPAENVIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYL 146

Human   190 RELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYS------- 247
            ||||||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   147 RELNVITETQCTLGLTALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYSITTGEIQ 211

Human   248 -----------QMQQQNTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQV 301
                       ||||||||||||||||||||||||||||||||||||||||||||||||||||||
 Frog   212 NEVCDQDETGKQMQQQNTQKVEASKVPEYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQV 276

Human   302 PQGKYKVLPTERTKVSSYPVALIPGQFQEYYKRYSPDELRYLPLNTALYEP---PLDPELPALDS 363
            ||||||:||:|.||||.|||:|||||||||||||||:||||||||||||||   ||||||..|||
 Frog   277 PQGKYKILPSEMTKVSPYPVSLIPGQFQEYYKRYSPNELRYLPLNTALYEPPLDPLDPELLTLDS 341

Human   364 DGDSDDGEDGRGDEKRKNK---------------------------------------------- 382
            |||||:.|:.: .||:|||
 Frog   342 DGDSDEVEEVK-SEKKKNKVSSDSSSVNMSESDNTQDTQEETPQPRPKVKEKSSTPRKEGSKRSV 405

Human   383 ------GTSPKVIPNAICGICLKGKESNKKGKAESLIHCSQCENSGHPSCLDMTMELVSMIKTYP 441
                  |..||..||||||||||||::||||::|.|||||||:||||||||||:.|||::||.||
 Frog   406 LSKSVSGYKPKSNPNAICGICLKGKDANKKGRSERLIHCSQCDNSGHPSCLDMSPELVTVIKKYP 470

Human   442 WQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTFCVGLGAIPSGRWICDCCQRAPPTPRKVGRRG 506
            |||||||||||||||||||||||||.||||||||||||||:|||||||||||..|.||:|..|:.
 Frog   471 WQCMECKTCIICGQPHHEEEMMFCDTCDRGYHTFCVGLGALPSGRWICDCCQNVPSTPKKGARKV 535

Human   507 KNSKEG 512
            ||||||
 Frog   536 KNSKEG 541

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHF10	XP_054211755.1	WH_NTD_PHF10	139..227	CDD:411035	86/87 (99%)
		PHD1_PHF10	393..447	CDD:277003	42/53 (79%)
		PHD2_PHF10	449..492	CDD:277004	40/42 (95%)
phf10	XP_012818532.1	WH_NTD_PHF10	96..184	CDD:411035	86/87 (99%)
		PHD1_PHF10	422..476	CDD:277003	42/53 (79%)
		PHD2_PHF10	478..521	CDD:277004	40/42 (95%)