Protein Alignment PHF10 and phf10

DIOPT Version :10

• Sequence 1: XP_054211755.1
• Gene: PHF10 / 55274
• HGNCID: 18250
• Length: 512
• Species: Homo sapiens
• Sequence 2: NP_956949.3
• Gene: phf10 / 393628
• ZFINID: ZDB-GENE-040426-1573
• Length: 490
• Species: Danio rerio
• Alignment Length: 484
• Identity: 354/484 - (73%)
• Similarity: 392/484 - (80%)
• Gaps: 58/484 - (11%)

Human    75 AALSPRPCDSDPATPGAQSPKDDNEDNSNDGTQPSKRRRMGSGDSSRSCETSSQDLGFSYYPAEN 139
            |.||||||||:|||||.||.|||.|:||:||:|..||||||||||||||:||:.:||.:|:||||
Zfish     3 AVLSPRPCDSNPATPGTQSIKDDIEENSSDGSQAPKRRRMGSGDSSRSCDTSTHELGPTYFPAEN 67

Human   140 LIEYKWPPDETGEYYMLQEQVSEYLGVTSFKRKYPDLERRDLSHKEKLYLRELNVITETQCTLGL 204
            |.|||||||:|||||||||||||||||||||||||::|||||||||||||||.||||||||||||
Zfish    68 LTEYKWPPDDTGEYYMLQEQVSEYLGVTSFKRKYPEMERRDLSHKEKLYLREQNVITETQCTLGL 132

Human   205 TALRSDEVIDLMIKEYPAKHAEYSVILQEKERQRITDHYKEYS------QMQQQNTQKVEASKVP 263
            |||||||||||||||||||||||||||||:||||||   |||:      ||||||.|||||||||
Zfish   133 TALRSDEVIDLMIKEYPAKHAEYSVILQERERQRIT---KEYNVSTLSVQMQQQNPQKVEASKVP 194

Human   264 EYIKKAAKKAAEFNSNLNRERMEERRAYFDLQTHVIQVPQGKYKVLPTERTKVSSYPVALIPGQF 328
            ||||||||||||||||.|||||||||||||||||:|||||||||:||.||||...:|||||||||
Zfish   195 EYIKKAAKKAAEFNSNFNRERMEERRAYFDLQTHIIQVPQGKYKILPPERTKTGPFPVALIPGQF 259

Human   329 QEYYKRYSPDELRYLPLNTALYEPPLDPELPALDSDGDSDDGEDGRGDEKRKNKGTS-------- 385
            |||||||||:|||||||||||:||||||||||||||||||||:||:.|.| ||||:|
Zfish   260 QEYYKRYSPNELRYLPLNTALFEPPLDPELPALDSDGDSDDGDDGKEDGK-KNKGSSDSSSGNTS 323

Human   386 ----------------------------------------PKVIPNAICGICLKGKESNKKGKAE 410
                                                    ||||||||||||.||||:||:||.|
Zfish   324 DGDSQDSGIHSKVKSKDRPGAQSKDGTPRSIQHKSVPGYKPKVIPNAICGICQKGKEANKRGKPE 388

Human   411 SLIHCSQCENSGHPSCLDMTMELVSMIKTYPWQCMECKTCIICGQPHHEEEMMFCDMCDRGYHTF 475
            :|||||||:||||||||||:::||:.||.|||||||||||.:|.||||||||||||.||||:|||
Zfish   389 ALIHCSQCQNSGHPSCLDMSVDLVAKIKMYPWQCMECKTCTVCQQPHHEEEMMFCDKCDRGFHTF 453

Human   476 CVGLGAIPSGRWICDCCQRAPPTPRKVGR 504
            |||:.:||.|.|:||.|.:...||:|.|:
Zfish   454 CVGMDSIPMGCWVCDLCSKDISTPQKKGQ 482

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
PHF10	XP_054211755.1	WH_NTD_PHF10	139..227	CDD:411035	82/87 (94%)
		PHD1_PHF10	393..447	CDD:277003	41/53 (77%)
		PHD2_PHF10	449..492	CDD:277004	31/42 (74%)
phf10	NP_956949.3	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..61		43/57 (75%)
		WH_NTD_PHF10	67..155	CDD:411035	82/87 (94%)
		SAY	83..292		186/211 (88%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	284..362		27/78 (35%)
		PHD1_PHF10	371..425	CDD:277003	41/53 (77%)
		PHD2_PHF10	427..470	CDD:277004	31/42 (74%)