Protein Alignment KIRREL1 and DIP-epsilon

DIOPT Version :9

• Sequence 1: XP_005245362.1
• Gene: KIRREL1 / 55243
• HGNCID: 15734
• Length: 773
• Species: Homo sapiens
• Sequence 2: NP_001137799.1
• Gene: DIP-epsilon / 7354433
• FlyBaseID: FBgn0259714
• Length: 467
• Species: Drosophila melanogaster
• Alignment Length: 530
• Identity: 105/530 - (19%)
• Similarity: 161/530 - (30%)
• Gaps: 212/530 - (40%)

Human    10 TLSDTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQGLKAW----- 69
            ||::..|:..:  |:....:.||.||:...|.|.:.|               :|....||
  Fly    43 TLNNVISEDPE--FTDVIENITVPAGRNVKLACSVKN---------------LGSYKVAWMHFEQ 90

Human    70 --------------PRYRVVGSADAGQ--YNLEITDAELSDDASYECQATEAALRSRRAKLTVLI 118
                          ||..|........  :.|.|.:.:..|...|.||......:::...:.|::
  Fly    91 SAILTVHNHVITRNPRISVTHDKHDKHRTWFLHINNVQEEDRGRYMCQINTVTAKTQYGFVKVVV 155

Human   119 PPE-DTRIDGGPVILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTV 182
            ||. |..:....:| ::.|....|.|:| ...|..||.|.||               ||
  Fly   156 PPNIDDALTSSDII-VREGDNVTLRCKA-KGSPEPTIKWKRD---------------DG------ 197

Human   183 SQLLINPTDLDIGRVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQAT 247
            ::::||.|                          |:||...|.:|.:        ||:
  Fly   198 NKIVINKT--------------------------LEVHDLETDSLEL--------ERI------- 221

Human   248 ANPEILGYRWAKGGFLIEDAHESRYETNVDYSFFTEPVSCEVHNKV-GSTNVSTLVNVHFAPRIV 311
                   .|...|.:|                       |...|.| .|.:....|:|.|:|.:.
  Fly   222 -------SRLHMGAYL-----------------------CIASNGVPPSVSKRIKVSVDFSPMVW 256

Human   312 VDPKPTTTDIGSDVTLTCVWVGNPPLTLTWTKKDSNMGPRP--------PGSPPEAALSAQVLSN 368
            :..:.....||.::||.|....||.....||:::..|....        ||.|...|
  Fly   257 IPHQLVGIPIGFNITLECFIEANPTSLNYWTRENDQMITESSKYKTETIPGHPSYKA-------- 313

Human   369 SNQLLLKSVTQADAGTYTCRAIVPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGS 433
            :.:|.:.:|..:|.|.|.|.|..|| |..:..:.||::.||.                      :
  Fly   314 TMRLTITNVQSSDYGNYKCVAKNPR-GDMDGNIKLYMSSPPT----------------------T 355

Human   434 TPPPDRIAWAWKENFLEVGTLERYTVER-------------------------TNS--GSGVLST 471
            .|||            ...||.|.|...                         |||  .||..|.
  Fly   356 QPPP------------TTTTLRRTTTTAAEIALDGYINTPLNGNGIGIVGEGPTNSVIASGKSSI 408

Human   472 LTINNVMEAD 481
            ..::|:.|.|
  Fly   409 KYLSNLNEID 418

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
KIRREL1	XP_005245362.1	I-set	22..116	CDD:254352	20/114 (18%)
		Ig	25..116	CDD:299845	19/111 (17%)
		Ig2_KIRREL3-like	138..219	CDD:143236	15/80 (19%)
		I-set	223..304	CDD:254352	12/81 (15%)
		Ig_2	227..305	CDD:290606	11/78 (14%)
		Ig_2	311..405	CDD:290606	25/101 (25%)
		IG_like	314..405	CDD:214653	25/98 (26%)
		Ig5_KIRREL3	407..504	CDD:143306	18/102 (18%)
		IG_like	416..504	CDD:214653	16/93 (17%)
DIP-epsilon	NP_001137799.1	IG_like	59..155	CDD:214653	20/110 (18%)
		Ig	69..139	CDD:143165	14/84 (17%)
		IG_like	165..249	CDD:214653	31/177 (18%)
		IGc2	172..237	CDD:197706	27/157 (17%)
		IG_like	267..348	CDD:214653	23/89 (26%)
		Ig	270..339	CDD:299845	21/77 (27%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3510
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
User_Submission	0	0.000	Not matched by this tool.
	2	1.810