DRSC/TRiP Functional Genomics Resources

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Protein Alignment KIRREL1 and kirrel1b

DIOPT Version :10

Sequence 1:XP_005245362.1 Gene:KIRREL1 / 55243 HGNCID:15734 Length:773 Species:Homo sapiens
Sequence 2:XP_017212964.1 Gene:kirrel1b / 100170816 ZFINID:ZDB-GENE-070912-173 Length:801 Species:Danio rerio


Alignment Length:835 Identity:465/835 - (55%)
Similarity:577/835 - (69%) Gaps:108/835 - (12%)


- Green bases have known domain annotations that are detailed below.


Human     6 VWILTLS-----DTFSQGTQTRFSQEPADQTVVAGQRAVLPCVLLNYSGIVQWTKDGLALGMGQG 65
            :||:||:     ..||   ..|||||||||:||.|:|.||.||:.||:|||||||||||||:|:.
Zfish     8 LWIVTLAIISVHRVFS---GPRFSQEPADQSVVIGERVVLSCVVFNYTGIVQWTKDGLALGIGED 69

Human    66 LKAWPRYRVVGSADAGQYNLEITDAELSDDASYECQATEAALRSRRAKLTVLIPPEDTRIDGGPV 130
            |:|||||||:...|.||||||||.|:|:||:.|||||||||||||||||||||||:...|:|.|.
Zfish    70 LRAWPRYRVLRIMDVGQYNLEITSADLTDDSLYECQATEAALRSRRAKLTVLIPPDGPVIEGSPE 134

Human   131 ILLQAGTPHNLTCRAFNAKPAATIIWFRDGTQQEGAVASTELLKDGKRETTVSQLLINPTDLDIG 195
            |||.|||..||||.:..|||.:||.|::||...|||..|||:|.|.||.||.|.|.|.|.|.|.|
Zfish   135 ILLTAGTSFNLTCVSRGAKPMSTIEWYKDGIIVEGAHTSTEVLSDRKRVTTKSFLEIQPMDTDTG 199

Human   196 RVFTCRSMNEAIPSGKETSIELDVHHPPTVTLSIEPQTVQEGERVVFTCQATANPEILGYRWAKG 260
            |.|||.:.|.|.|.||.:::.|::||||||.|||||::|.|||||.|||||||||.|:|||||||
Zfish   200 RNFTCVASNLAAPLGKRSTVTLNIHHPPTVILSIEPRSVLEGERVKFTCQATANPPIMGYRWAKG 264

Human   261 GFLIEDAHESRYETNVDYSFFTEPVSCEVHNKVGSTNVSTLVNVHFAPRIVVDPKPTTTDIGSDV 325
            |.:::.|.||.:||..|:|||||||||.|.|.|||||||.||:|||.|.:||:|:|.|.|:.|||
Zfish   265 GVILDGARESVFETTADHSFFTEPVSCLVFNAVGSTNVSILVDVHFGPILVVEPRPVTVDVDSDV 329

Human   326 TLTCVWVGNPPLTLTWTKKDSNMGPRPPGSPPEAALSAQVLSNSNQLLLKSVTQADAGTYTCRAI 390
            ||.|.|.||||||||||||.|:|                ||||||||.||||:|||||.|.|:||
Zfish   330 TLNCKWSGNPPLTLTWTKKGSSM----------------VLSNSNQLFLKSVSQADAGQYVCKAI 378

Human   391 VPRIGVAEREVPLYVNGPPIISSEAVQYAVRGDGGKVECFIGSTPPPDRIAWAWKENFLEV--GT 453
            ||||||.|.||.|.||||||||||.:||||||:.|:::|:|.||||||:|.||||||..|.  ||
Zfish   379 VPRIGVGETEVTLTVNGPPIISSEPIQYAVRGEKGEIKCYIASTPPPDKIVWAWKENVWEKERGT 443

Human   454 -LERYTVERT---NSGSGVLSTLTINNVMEADFQTHYNCTAWNSFGPGTAIIQLEE-----REVL 509
             |||||||::   ..|..||||||||||||||||:.|||||||:|||||.||.|||     .:::
Zfish   444 LLERYTVEQSRPATQGGAVLSTLTINNVMEADFQSTYNCTAWNAFGPGTMIITLEETDIASEDIV 508

Human   510 PVGIIAGATIGASILLIFFFIALVFFLYRRRKGSRKDVTLRKLDIKVETVNREPLTMHSDREDDT 574
            |||:|||.::|:||||:....||:|:|||:||.||:.||| |.||||||||:|     ::.|::.
Zfish   509 PVGVIAGGSVGSSILLLLLLFALIFYLYRQRKSSRRGVTL-KPDIKVETVNKE-----TNLEEEA 567

Human   575 ASVSTATRVMKAIYS------------SFKDDVDLKQDLRCDTIDTR-EEYEMKDPTNGYYNVRA 626
            ||.|||||::||:||            .||||:||||||:.:|::.: ||||.||||||||||||
Zfish   568 ASASTATRMVKAMYSFLPSVSLSPSTQPFKDDMDLKQDLQTETLEPKVEEYEAKDPTNGYYNVRA 632

Human   627 --HED-RPSSRAVLYADYRAPGPA------------------RFDGRPSSRLSHSSGYAQLNTYS 670
              |:: |.|:|::||.::|||.||                  |::.||:||::|:: ||..||.:
Zfish   633 TTHDEVRSSTRSLLYQEFRAPNPASVSASTGGPANIHPAPTGRYEARPTSRMAHNT-YAHFNTIA 696

Human   671 RGPASDYGPEPTPPG-----PAAPAGTDTTSQLSYENYEKFNSHPFPGAAGYPTYRLGYPQAPPS 730
            |  ||...|...|..     ||.....::|:.|::::|....:         |.||||:  ||| 
Zfish   697 R--ASQIQPPANPVSKTTDYPAERGLLESTNPLAFDSYAYSTT---------PQYRLGF--APP- 747

Human   731 GLERTP-YEAYDP-----------IGKYATATRFSYTSQHSDYGQRFQQRMQTHV 773
             ||..| ||.|..           :|||.::.:|.|::..::|.||..|||||||
Zfish   748 -LEAGPAYEMYPTGQGVGTSQDANVGKYPSSAQFPYSTPPTEYSQRHTQRMQTHV 801

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
KIRREL1XP_005245362.1 Ig 22..116 CDD:472250 71/93 (76%)
Ig strand B 38..42 CDD:409353 2/3 (67%)
Ig strand C 51..54 CDD:409353 2/2 (100%)
Ig strand E 78..87 CDD:409353 6/8 (75%)
Ig strand F 97..102 CDD:409353 3/4 (75%)
Ig strand G 109..112 CDD:409353 2/2 (100%)
IgI_2_KIRREL3-like 122..219 CDD:409416 50/96 (52%)
Ig strand A 123..126 CDD:409416 0/2 (0%)
Ig strand A' 129..133 CDD:409416 2/3 (67%)
Ig strand B 140..147 CDD:409416 4/6 (67%)
Ig strand C 152..157 CDD:409416 2/4 (50%)
Ig strand C' 160..162 CDD:409416 1/1 (100%)
Ig strand D 165..172 CDD:409416 4/6 (67%)
Ig strand E 179..187 CDD:409416 4/7 (57%)
Ig strand F 196..204 CDD:409416 4/7 (57%)
Ig strand G 210..216 CDD:409416 2/5 (40%)
Ig_3 222..291 CDD:464046 49/68 (72%)
Ig_3 308..389 CDD:464046 47/80 (59%)
IgI_5_KIRREL3 407..504 CDD:409479 71/102 (70%)
Ig strand A 408..412 CDD:409479 3/3 (100%)
Ig strand A' 414..417 CDD:409479 1/2 (50%)
Ig strand B 425..432 CDD:409479 2/6 (33%)
Ig strand C 439..444 CDD:409479 2/4 (50%)
Ig strand C' 446..449 CDD:409479 2/2 (100%)
Ig strand D 457..464 CDD:409479 4/9 (44%)
Ig strand E 467..474 CDD:409479 5/6 (83%)
Ig strand F 485..492 CDD:409479 5/6 (83%)
Ig strand G 495..502 CDD:409479 5/6 (83%)
kirrel1bXP_017212964.1 Ig 25..120 CDD:472250 71/94 (76%)
Ig strand B 42..46 CDD:409387 2/3 (67%)
Ig strand C 55..58 CDD:409387 2/2 (100%)
Ig strand E 82..86 CDD:409387 1/3 (33%)
Ig strand F 101..106 CDD:409387 3/4 (75%)
Ig strand G 113..116 CDD:409387 2/2 (100%)
Ig 127..223 CDD:472250 50/95 (53%)
Ig strand B 143..147 CDD:409416 2/3 (67%)
Ig strand C 157..161 CDD:409416 2/3 (67%)
Ig strand E 187..191 CDD:409416 2/3 (67%)
Ig strand F 201..206 CDD:409416 3/4 (75%)
Ig strand G 216..219 CDD:409416 0/2 (0%)
Ig_3 226..>286 CDD:464046 41/59 (69%)
Ig_3 312..377 CDD:464046 47/80 (59%)
IgI_5_KIRREL3 395..498 CDD:409479 71/102 (70%)
Ig strand A 396..400 CDD:409479 3/3 (100%)
Ig strand A' 402..405 CDD:409479 1/2 (50%)
Ig strand B 413..420 CDD:409479 2/6 (33%)
Ig strand C 427..432 CDD:409479 2/4 (50%)
Ig strand C' 434..437 CDD:409479 2/2 (100%)
Ig strand D 448..455 CDD:409479 4/6 (67%)
Ig strand E 461..468 CDD:409479 5/6 (83%)
Ig strand F 479..486 CDD:409479 5/6 (83%)
Ig strand G 489..496 CDD:409479 5/6 (83%)

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